Can Artificial Knee Replacement Be Done After Recurrent Cellulitis? - Orthopedics

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Can a person with cellulitis in both legs undergo knee replacement surgery?


My father-in-law is 84 years old and has experienced recurrent cellulitis in both lower legs twelve times over the past six years, with six of those episodes requiring hospitalization due to severe fever.
Recently, the duration of each episode has been increasing, and the recovery time has also lengthened.
The most recent episode occurred on October 5th, and he is still on medication for control.
Additionally, he receives a long-acting antibiotic injection once a month.
(His overall health is very good.) However, the cartilage in both of his knees has already worn down, and he has been hesitant to undergo knee replacement surgery due to the recurrent infections in his legs.

I would like to ask Dr.
Shi, given his condition, how long should we observe him after his inflammatory episodes are controlled before considering knee replacement surgery? If surgery is possible, what are the associated risks? Alternatively, is he not a suitable candidate for surgery? Based on your professional experience, we would appreciate your advice.
Thank you for taking the time to answer my questions!

Xue Xiaojie, 40~49 year old female. Ask Date: 2010/11/27

Dr. Shi Guozheng reply Orthopedics


If there is cellulitis in the leg that cannot be controlled, it is not suitable to perform joint replacement surgery.
Typically, observation is required for about six weeks, and if the inflammatory markers return to normal levels, then the surgery is more appropriate.
The risks of surgery include infection, vascular occlusion, or poor wound healing, among others.

Reply Date: 2010/11/27

More Info


When considering knee replacement surgery for an elderly patient with a history of recurrent cellulitis, several factors must be taken into account. Your father-in-law's situation is complex due to his recurrent infections, which can significantly impact both the timing and the safety of a total knee arthroplasty (TKA).

1. Timing for Surgery After Cellulitis:
The primary concern with recurrent cellulitis is the risk of infection during and after surgery. Ideally, the patient should be free of any active infections for a significant period before undergoing elective surgery. In general, a waiting period of at least 3 to 6 months after the last episode of cellulitis is recommended, assuming that the infection has been adequately treated and controlled. This allows time for the body to stabilize and reduces the risk of postoperative infections.

2. Risks Associated with Surgery:
Knee replacement surgery carries inherent risks, particularly in patients with a history of recurrent infections. These risks include:
- Infection: The most significant concern is the risk of surgical site infection, which can be exacerbated in patients with a history of cellulitis. Even with prophylactic antibiotics, the risk remains higher in such patients.

- Delayed Healing: Older adults may experience slower healing processes, which can complicate recovery.

- Complications from Anesthesia: Given his age, there may be additional risks associated with anesthesia, including cardiovascular complications.

- Thromboembolic Events: Patients with limited mobility post-surgery are at increased risk for blood clots, which can lead to deep vein thrombosis (DVT) or pulmonary embolism (PE).

3. Suitability for Surgery:
Determining whether your father-in-law is a suitable candidate for knee replacement involves a comprehensive evaluation by an orthopedic surgeon. This evaluation should include:
- A thorough medical history and physical examination.

- Assessment of his current health status, including any underlying conditions that may affect surgery and recovery.

- Imaging studies (like X-rays or MRIs) to evaluate the extent of cartilage loss and joint damage.

- Consultation with an infectious disease specialist may be warranted to assess his history of cellulitis and to develop a plan for managing infection risk.

4. Recommendations:
Given your father-in-law's situation, here are some recommendations:
- Infection Control: Work closely with his healthcare team to ensure that his cellulitis is well-managed and that he is on an appropriate long-term antibiotic regimen. This may involve regular follow-ups with his primary care physician or an infectious disease specialist.

- Orthopedic Consultation: Schedule a consultation with an orthopedic surgeon who specializes in knee replacements. Discuss the history of cellulitis and any concerns about surgery. The surgeon may recommend additional preoperative measures, such as optimizing his health and possibly adjusting his antibiotic regimen.

- Physical Therapy: Engaging in physical therapy may help improve his mobility and strength, which can be beneficial both pre- and post-surgery.

- Monitoring: Regular monitoring of his condition is essential. If he experiences any new symptoms or recurrent infections, these should be addressed promptly.

In summary, while knee replacement surgery can be performed after recurrent cellulitis, careful consideration and planning are crucial. The decision should be made collaboratively with his healthcare team, weighing the risks and benefits based on his overall health and the control of his infection history.

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