Thickened Endometrium: Signs of Early Pregnancy? - Obstetrics and Gynecology

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Endometrial thickening and its impact on conception?


Hello, I visited a doctor at the beginning of October to discuss having a second child.
After giving birth to my first child in 1997, I experienced irregular menstruation.
The doctor prescribed progesterone for me to take one tablet in the morning and one in the evening starting from October 14 for a total of 10 days.
My menstruation started on October 26.
On the third day of my period, I took ovulation medication, two tablets a day for five days.
The doctor advised my husband and me to try to conceive on November 12, 14, and 16.
However, since I was more tired on the 16th, we took a break that day.
My husband wanted to increase the chances of conception, so we had intercourse almost every day in November.
The schedule was as follows: November 1, 2, 4, 8, 11, 12, 14, 19, 23, 26, 29, and 30, as well as December 4.
On November 29, since my period had not arrived, I went to the hospital for a check-up.
A urine test indicated that I was not pregnant, but I experienced cramping in my lower abdomen, so the doctor performed an ultrasound.
The ultrasound showed that my endometrium was thickened, and the doctor did not prescribe any medication, advising me to wait for two weeks at home.
During this time, I noticed some changes in my body, including small pimples on my face, nausea after meals, and increased fatigue and sleepiness.

I would like to ask:
1.
Is a thickened endometrium indicative of pregnancy within a month? (I heard from a mother that she read in a magazine that a thickened endometrium suggests pregnancy within a month.)
2.
Since the urine test showed no pregnancy and the ultrasound only revealed a thickened endometrium, does the absence of menstruation during the waiting period increase the chances of conception?
3.
Are there cases where a person is pregnant for 1 to 2 months but the urine test does not detect it?

RARA, 20~29 year old female. Ask Date: 2010/12/09

Dr. Dong Yuhong reply Obstetrics and Gynecology


Hello: If your period still hasn't arrived, it's important to take a urine test to check for the possibility of pregnancy.
A thickened endometrium may indicate a chance of pregnancy, but it does not necessarily mean that you are pregnant.
It's understandable to feel anxious about wanting to conceive; I recommend trying to relax and cooperate with the treatment plan provided by your healthcare provider, as this may increase your chances of a successful pregnancy.
Thank you!

Reply Date: 2010/12/09

More Info


Understanding the thickening of the endometrium and its implications for early pregnancy can be quite complex. Based on your situation, let's address your questions systematically.

1. Thickened Endometrium and Early Pregnancy: The endometrium, which is the lining of the uterus, naturally thickens in preparation for a potential pregnancy. This thickening occurs due to the influence of hormones, particularly estrogen and progesterone. If fertilization occurs, the thickened endometrium provides a suitable environment for the implantation of the embryo. Therefore, a thickened endometrium can indeed be a sign of early pregnancy, but it is not definitive on its own. It is important to note that a thickened endometrium can also occur due to other factors, such as hormonal imbalances or conditions like endometrial hyperplasia.

2. Negative Urine Test and Thickened Endometrium: A negative urine pregnancy test, especially if taken too early, does not rule out pregnancy. Urine tests detect the hormone hCG (human chorionic gonadotropin), which is produced after implantation. If implantation has not yet occurred, or if it is very early, the levels of hCG may not be high enough to be detected. The fact that your ultrasound showed a thickened endometrium suggests that your body is preparing for a potential pregnancy. If your menstrual period has not arrived and you are experiencing symptoms like nausea and fatigue, it may indicate that you are in the early stages of pregnancy, even if the urine test was negative.

3. Early Pregnancy Detection Challenges: It is indeed possible for a urine pregnancy test to yield a negative result even when a woman is pregnant, particularly in the first few weeks after conception. This can happen if the test is taken too early, before the body has produced enough hCG. In some cases, women may not get a positive result until several days after a missed period. If you suspect you might be pregnant, it is advisable to wait a few days and retest or consult with your healthcare provider for a blood test, which is more sensitive and can detect lower levels of hCG.

In summary, a thickened endometrium can be a sign of early pregnancy, but it is not conclusive on its own. The negative urine test does not eliminate the possibility of pregnancy, especially if taken early. If your menstrual cycle is delayed and you are experiencing symptoms consistent with pregnancy, it would be prudent to follow up with your healthcare provider for further evaluation, including a blood test and possibly a repeat ultrasound.
Additionally, maintaining a healthy lifestyle, including a balanced diet rich in folic acid, iron, and other essential nutrients, is crucial when trying to conceive. If you have any underlying health conditions or concerns about your menstrual cycle, discussing these with your doctor can provide you with tailored advice and support.

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