Should My Brother Undergo Surgery for Stage IV Tongue Cancer? - Oncology

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Should surgery be performed?


My brother, who is 55 years old, was diagnosed with stage IV base of tongue cancer in July.
After undergoing 35 sessions of radiation therapy and four months of chemotherapy, he developed severe throat ulcers that led to significant bleeding, necessitating a tracheostomy.
He has already undergone a gastrostomy.
Despite all these treatments, his condition has not improved.
The doctor mentioned that he has throat ulcers and residual cancer cells, so a total laryngectomy is required.

Could you please advise if there are any medications that can help heal the throat wounds so he can continue with chemotherapy? What are the potential long-term complications of the surgery? Thank you.

Mi Mi Mao, 50~59 year old female. Ask Date: 2010/12/23

Dr. Chen Junyi reply Oncology


Wound healing may require a discussion regarding the possibility of residual tumor presence, and detailed aspects may need to be addressed.

Reply Date: 2010/12/23

More Info


When considering whether your brother should undergo surgery for Stage IV tongue cancer, several factors must be taken into account, including the current state of his health, the extent of the disease, and the potential benefits and risks associated with surgery.

Stage IV tongue cancer is often characterized by significant local invasion and the potential for metastasis. In your brother's case, the fact that he has undergone extensive radiation therapy and chemotherapy, yet continues to experience severe complications such as throat ulceration and significant bleeding, indicates that the cancer is aggressive and may not be responding adequately to these treatments. The presence of residual cancer cells, as noted by his physician, further complicates the situation and suggests that more aggressive intervention may be necessary.

The recommendation for a total laryngectomy (complete removal of the larynx) is a common approach in cases where there is significant local disease that cannot be managed effectively through other means. This surgery can help to remove the cancerous tissue and potentially improve quality of life by alleviating symptoms caused by the tumor. However, it is important to understand the implications of such a procedure.

Potential Benefits of Surgery:
1. Removal of Cancer: The primary goal of the surgery is to remove the cancerous tissue, which may help to control the disease and prevent further complications.

2. Symptom Relief: By removing the tumor, the surgery may alleviate symptoms such as pain, difficulty swallowing, and breathing problems caused by the tumor's presence.

Potential Risks and Complications:
1. Loss of Voice: A total laryngectomy will result in the loss of the natural voice, as the larynx is responsible for sound production. Patients typically learn alternative methods of communication post-surgery.

2. Changes in Swallowing: The surgery may affect swallowing, leading to the need for dietary modifications or rehabilitation.

3. Tracheostomy: A permanent tracheostomy may be necessary, which involves creating an opening in the neck to facilitate breathing.

4. Psychological Impact: The physical changes and loss of voice can have significant psychological effects, requiring support and counseling.

Regarding the healing of throat wounds and the continuation of chemotherapy, there are no specific medications that can guarantee wound healing in the context of ongoing cancer treatment. However, supportive care measures, including proper nutrition, hydration, and possibly topical treatments, may help improve healing. It is crucial to discuss these options with the healthcare team, as they can provide tailored recommendations based on your brother's specific condition.

In terms of postoperative recovery, the extent of complications can vary widely among individuals. Some patients may experience significant challenges, while others may adapt well to the changes. The healthcare team will provide guidance on rehabilitation and support services to help your brother adjust to life after surgery.

Ultimately, the decision to proceed with surgery should be made collaboratively with the healthcare team, taking into account your brother's overall health, the potential for recovery, and his personal preferences. It may also be beneficial to seek a second opinion from another oncologist or surgical specialist to ensure that all treatment options are thoroughly explored.
In conclusion, while surgery may present risks and challenges, it could also offer a chance for improved quality of life and disease control in the face of advanced tongue cancer. Open communication with the medical team and careful consideration of all factors will be essential in making the best decision for your brother's care.

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