Yellowing Eyes: Causes, Symptoms, and Solutions - Ophthalmology

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Yellowing of the sclera with tenderness?


Hello Doctor: My left eye's sclera has been turning yellow since February of this year, and it has spread to the other eye.
Initially, the yellowing was mainly under the cornea, but it has extended to the upper half of the eye, with the lower part being more noticeably yellow (in both eyes).
Now, sometimes when I wear glasses, my eyes feel very strained.
Additionally, at night when I go to bed, I used to be able to see things in the room slightly from the faint light outside just a few seconds after turning off the lights, but recently it takes several minutes to achieve normal clarity, as if my pupils have become less responsive.
I've also been experiencing severe headaches, especially with my upcoming graduate school exams, and I really want to study, but I can't keep my eyes open for long without discomfort.
I can't wear glasses while reading because it makes the strain worse.
I've seen many doctors, but none have been able to help, and I'm losing confidence in my eyesight.
Lastly, I've noticed that several people around me (including my parents and younger brother) also have yellowing eyes, which makes me wonder if I might have contracted something...
I really need the assistance of a doctor.
Thank you, Doctor.

Phoebus, 20~29 year old female. Ask Date: 2010/12/28

Dr. Ke Meilan reply Ophthalmology


I think you are too tired.
Additionally, yellowing of the sclera can indicate liver function issues; if liver function tests are normal, there is no need to worry too much, as this is not an infectious disease.
Putting too much pressure on yourself while studying can actually deplete your energy.
Just do your best on the exam and try not to overthink.
Wishing you health and peace.
Ophthalmologist - Dr.
Mei-Lan Ke

Reply Date: 2010/12/28

More Info


Yellowing of the eyes, also known as scleral icterus, is a condition that can be alarming and is often associated with various underlying health issues. The yellowing occurs due to an accumulation of bilirubin, a byproduct of the breakdown of red blood cells. When the liver is unable to process bilirubin effectively, it can lead to jaundice, which manifests as yellowing of the skin and eyes.

In your case, the gradual yellowing of your eyes since February, along with symptoms such as eye strain, difficulty adjusting to darkness, and headaches, suggests that it is essential to investigate the underlying cause. While you mentioned that several family members also have yellow eyes, it is important to note that jaundice is not contagious. Instead, it may indicate a shared genetic predisposition or environmental factors affecting liver function.

The first step in addressing your concerns is to evaluate your liver function. A simple blood test can measure liver enzymes, bilirubin levels, and other markers to determine if your liver is functioning properly. If your liver function tests return normal, it may indicate that the yellowing is not due to liver disease but could be related to other factors such as dietary habits, medications, or even conditions like pinguecula or pterygium, which are benign growths on the conjunctiva that can appear yellowish.

Your symptoms of eye strain and difficulty focusing, especially when wearing glasses, may be related to visual fatigue or an uncorrected refractive error, particularly since you mentioned having presbyopia (age-related difficulty in focusing on close objects). It is crucial to ensure that your prescription is up to date and that you are using the correct lenses for your vision needs. Additionally, prolonged study sessions without breaks can lead to digital eye strain, which can exacerbate feelings of discomfort and fatigue.

The sensation of your pupils not responding quickly to changes in light could be a sign of fatigue or a temporary issue with your visual system. It is not uncommon for individuals under stress, such as preparing for exams, to experience increased eye strain and discomfort. Implementing the 20-20-20 rule—taking a 20-second break to look at something 20 feet away every 20 minutes—can help alleviate some of this strain.

If headaches persist, it is essential to consider other potential causes, such as tension headaches or migraines, which can be triggered by eye strain, stress, or changes in sleep patterns. Maintaining a regular sleep schedule, staying hydrated, and managing stress through relaxation techniques can be beneficial.

In summary, while yellowing of the eyes can be concerning, it is crucial to approach the situation systematically. Start with a thorough evaluation of your liver function and eye health. Ensure that your vision is properly corrected and take regular breaks during study sessions. If symptoms persist or worsen, seeking further evaluation from an ophthalmologist or a healthcare provider is advisable to rule out any serious conditions and to receive appropriate treatment. Remember, taking care of your overall health and managing stress is vital during this demanding time.

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