Hope for Malignant Melanoma: Seeking New Treatments in Taiwan - Oncology

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Malignant melanoma


My father has been diagnosed with malignant melanoma.
This is a rare disease that insurance companies are hesitant to cover, and doctors are at a loss for how to treat it! In Taiwan, cases are extremely rare, especially since my father's melanoma is located in internal organs, not on the skin.

On March 27, 2011, the Apple Daily reported on an Australian man who had melanoma that spread to his spinal cord, liver, and lungs.
After taking a new drug from GlaxoSmithKline in the United States, he experienced a miraculous recovery overnight and was discharged from the hospital four days later! Just yesterday, the latest report from Apple Daily reignited our family's hope!
We hope you can help ordinary citizens like us and save my father, who has worked hard all his life.
We need to know if major hospitals in Taiwan can apply to introduce this new drug! Please help save my father, who, like the Australian man, has been declared untreatable by the hospital.
If the hospital can legally obtain this medication to treat my father, he certainly has a chance to regain his health!
We sincerely request the assistance of the Department of Health to help us seek this medication that could save my father's life.
We are grateful for any support you can provide!

Chen Jian-sen, 30~39 year old female. Ask Date: 2011/03/29

Dr. Fan Sheng reply Oncology


Mr.
Chen: According to inquiries made with doctors at Taipei Veterans General Hospital, a drug provided by GlaxoSmithKline underwent human trials for the treatment of melanoma in Taiwan last year, but the trials were discontinued due to excessive toxicity.
It is possible that the drug mentioned by "Apple" is not the same one.
There may be new drugs being introduced, but currently, there are no new trials ongoing in Taiwan.
The Department of Health requires that any new drug must first pass human trials before it can be approved for a drug license.
This is to inform you.

Reply Date: 2011/03/29

More Info


I'm truly sorry to hear about your father's battle with malignant melanoma, especially given the complexities involved with internal organ involvement. Malignant melanoma is indeed a serious condition, and when it metastasizes to internal organs, it poses significant treatment challenges.
In Taiwan, the introduction of new drugs for treating conditions like malignant melanoma typically involves a rigorous process governed by the Ministry of Health and Welfare. This process includes clinical trials, safety evaluations, and efficacy assessments. The drug you mentioned, developed by GlaxoSmithKline, may have shown promise in other countries, but as noted in previous communications, it may not have been approved for use in Taiwan due to safety concerns or lack of sufficient clinical trial data.

For your father, the first step would be to consult with a medical oncologist who specializes in melanoma. They can provide insights into the latest treatment options available in Taiwan, including any clinical trials that may be ongoing. While it is unfortunate that some treatments may not be covered by insurance, there are often alternative therapies or newer drugs that may be available through compassionate use programs or clinical trials.

In the case of malignant melanoma, treatment options may include targeted therapies, immunotherapy, and chemotherapy. Targeted therapies, such as BRAF inhibitors, have shown effectiveness in patients with specific genetic mutations. Immunotherapy, particularly with agents like checkpoint inhibitors (e.g., pembrolizumab or nivolumab), has revolutionized the treatment landscape for melanoma and has been associated with significant survival benefits in many patients.

If your father is not currently enrolled in any clinical trials, it may be worthwhile to explore this option. Clinical trials often provide access to cutting-edge therapies that are not yet widely available. Additionally, hospitals in Taiwan may have partnerships with international research networks, which could facilitate access to new treatments.

It's also essential to consider supportive care options that can improve your father's quality of life during treatment. Palliative care services can provide symptom management and emotional support for both your father and your family.

In summary, while the situation is undoubtedly challenging, there are avenues to explore for potential treatment options. Engaging with a specialized oncologist and inquiring about clinical trials or new drug approvals can provide hope and possibly lead to effective treatment strategies for your father. I encourage you to remain proactive in seeking out information and support, as advancements in cancer treatment are continually evolving. Your father's health and well-being are paramount, and there are resources available to help navigate this difficult journey.

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