Can I Get the Quadrivalent Vaccine After HPV Treatment for CIN?

If you have already been infected with a different type of virus, can you receive the quadrivalent vaccine to protect against other types of the virus?

Hello, I would like to ask about my situation.
Last year, I had a Pap smear that showed abnormalities, and a biopsy confirmed CIN2.
I underwent a conization procedure as arranged by my doctor.
However, this month, my Pap smear showed abnormalities again, and the biopsy result was CIN1.
I also tested positive for HPV type 53.
I would like to know if I can still receive the quadrivalent vaccine to protect against other types of the virus.
Additionally, does having undergone a large loop excision procedure mean that I may not be completely cured? Could it be that my husband is still carrying the infection, as I have only been with him?

Zhang, 30~39 year old female. Ask Date: 2011/05/04

Dr. Cai Yonglong reply Obstetrics and Gynecology

Dear Dr.
Tsai Yong-Lung of the Tainan Hospital, Department of Obstetrics and Gynecology,
Vaccines are preventive measures, and there are four situations in which the cervical cancer vaccine should not be administered: (1) It should not be given during pregnancy (it can be administered after delivery).
(2) It should not be given if there is a fever of 38 degrees Celsius (100.4 degrees Fahrenheit) or higher (it can be administered once the fever subsides).
(3) It should not be given if another vaccine has been administered within the past month (as the T cells cannot produce that many antibodies simultaneously).
(4) It should not be given if the patient has a cervical lesion of CIN2 (including) or higher (it can be administered after treatment).

You have undergone a cone biopsy and tested positive for HPV type 53, with a follow-up showing CIN1.
Therefore, you are eligible to receive the vaccine.

(P.S.
The quadrivalent vaccine targets HPV types 6, 11, 16, and 18.)
Wishing you good health and all the best!

Reply Date: 2011/05/04

More Info

Yes, you can receive the quadrivalent HPV vaccine after treatment for CIN, even if you have had a previous diagnosis of CIN2 and subsequent treatment that resulted in a CIN1 diagnosis. The quadrivalent vaccine protects against HPV types 6, 11, 16, and 18, which are associated with genital warts and cervical cancer. Since you have already undergone treatment for CIN2 and are now classified as CIN1, it is advisable to discuss vaccination with your healthcare provider.

The effectiveness of the vaccine in individuals who have already been infected with HPV is a common concern. While the vaccine is primarily preventive, it can still provide benefits even if you have been exposed to certain HPV types. It is important to note that the vaccine will not treat existing infections or lesions but can help protect against other HPV types that you may not have been exposed to yet.

Regarding your concern about whether the treatment has been completely effective, it is essential to follow up with your healthcare provider for regular screenings. The fact that you have undergone a conization procedure (a type of cervical surgery) indicates that your healthcare team is actively managing your cervical health. It is also crucial to understand that HPV can persist in the body, and while your partner may not show symptoms, he could still be a carrier of the virus. Using protection during sexual activity, such as condoms, can help reduce the risk of transmission.

In terms of timing for the vaccination, it is generally recommended to wait until you have fully recovered from any surgical procedures and have received clearance from your healthcare provider. This ensures that your immune system is in the best condition to respond to the vaccine.

In summary, receiving the quadrivalent HPV vaccine after treatment for CIN is a viable option that can help protect against other HPV types. Regular follow-ups and screenings are essential for monitoring your cervical health, and discussing your vaccination options with your healthcare provider will help you make an informed decision.

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