Colorectal Polyps: Family Risk and Management Questions - Gastroenterology and Hepatology

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Colon polyp issues?


Hello, doctor.
My husband and I underwent a colonoscopy after 8 years of marriage.
Our child is 7 years old.
I am 28 years old, and my husband is 32.
He has three polyps, two of which are hyperplastic, and one has been removed and tested, all measuring less than 0.5 cm.
I have two polyps, also hyperplastic, measuring 0.4 cm, which do not require removal.

(1) I would like to ask if our child will be at risk of familial adenomatous polyposis (FAP), which is characterized by the development of hundreds of colorectal polyps starting in adolescence.
What methods are available for screening?
(2) We had our colonoscopies done at Huisheng Clinic, where the polyps were examined under 100x magnification, and both my husband’s and my polyps were determined to be hyperplastic with no cancer cells present.
Do you think removal is necessary? The doctors there said it is not needed.
(3) Are we at a higher risk of developing colorectal cancer compared to the general population?
(4) Do we need to undergo colonoscopies annually?
(5) Given that we are quite young to have colorectal polyps, could this be familial? However, none of our family members have had colorectal cancer.
Will our polyps continue to grow? If it is familial adenomatous polyposis, will the colon become filled with polyps? However, I read online that if it is familial, polyps would continue to grow during adolescence.
Considering my husband’s and my age, do we fall into the category of polyps due to poor dietary habits, or is it familial?

Ding Dong, 20~29 year old female. Ask Date: 2011/06/14

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Hello: Familial adenomatous polyposis (FAP) can result in dozens or even hundreds of gastrointestinal polyps, which are typically adenomatous rather than hyperplastic.
If a polyp is larger than 1 centimeter, removal is recommended.
For patients with a history of polyps, it is advised to undergo surveillance every 2 to 3 years after removal.
Wishing you good health.
Sincerely, Dr.
Chi-Feng Chen, Taoyuan General Hospital, Department of Health.

Reply Date: 2011/06/14

More Info


Understanding colorectal polyps and their implications for family risk is crucial, especially when there is a history of polyps or colorectal cancer in the family. Based on the information provided, let's address your questions systematically.

1. Risk of Family Members Developing Familial Adenomatous Polyposis (FAP): Familial Adenomatous Polyposis is a hereditary condition characterized by the development of hundreds to thousands of adenomatous polyps in the colon and rectum, typically starting in adolescence. However, based on your description, both you and your husband have only a few adenomatous polyps, which are classified as hyperplastic polyps. Hyperplastic polyps are generally considered benign and do not carry the same cancer risk as adenomatous polyps. Since there is no family history of colorectal cancer or polyps in your relatives, it is unlikely that your child will inherit a predisposition to FAP. Genetic testing can be performed if there is a strong family history of colorectal cancer or polyps, but in your case, it may not be necessary.

2. Need for Polyp Removal: The decision to remove polyps often depends on their type, size, and histological features. Hyperplastic polyps, especially those smaller than 1 cm, typically do not require removal unless there are atypical features. Since your husband’s polyps are small and have been confirmed as hyperplastic without any cancerous cells, the recommendation not to remove them seems appropriate. However, it is essential to have regular follow-ups to monitor any changes.

3. Increased Risk of Colorectal Cancer: Having polyps does increase the risk of developing colorectal cancer, but the degree of risk depends on the type of polyps. Adenomatous polyps have a higher risk of malignant transformation compared to hyperplastic polyps. Since both you and your husband have hyperplastic polyps, your risk is not significantly elevated compared to the general population. However, regular screening is still essential.

4. Frequency of Colonoscopies: Given your current situation, it is advisable to have follow-up colonoscopies every 3 to 5 years, rather than annually, unless new symptoms arise or if polyps are found that require closer monitoring. Regular screenings are crucial for early detection of any changes in the colon.

5. Family History and Lifestyle Factors: The presence of polyps at a young age can be concerning, but it does not automatically indicate a hereditary syndrome like FAP, especially in the absence of a family history of colorectal cancer. Lifestyle factors, such as diet, can contribute to the development of polyps. A diet high in red and processed meats and low in fiber may increase the risk of polyp formation. It is essential to maintain a healthy diet rich in fruits, vegetables, and whole grains to help reduce the risk of further polyp development.

In summary, while you and your husband have been diagnosed with hyperplastic polyps, the risk of familial adenomatous polyposis seems low given the absence of a family history of colorectal cancer. Regular monitoring through colonoscopy is essential, and maintaining a healthy lifestyle can help mitigate further risks. If you have any concerns or notice any changes in your bowel habits, do not hesitate to consult your healthcare provider for further evaluation.

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