Thickened Endometrium and Heavy Menstrual Bleeding - Obstetrics and Gynecology

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Thickened endometrium, resulting in heavy menstrual bleeding with each cycle?


Hello Doctor: Since the year before last, my menstrual cycle has become irregular.
Sometimes the flow is light, but it can last for two weeks without stopping.
I visited a gynecologist and took medication, but it resulted in heavy bleeding, and I had to go to the hospital for a dilation and curettage (D&C) to stop it.
I usually have very heavy menstrual bleeding, which often leads to iron deficiency, so I take iron supplements.
The doctor mentioned that my endometrium is too thick and I have previously used progesterone and birth control pills to regulate my cycle.
Could you please tell me if this is a sign of perimenopause?

Ying Ying, 50~59 year old female. Ask Date: 2011/06/19

Dr. Chen Changfu reply Obstetrics and Gynecology


Women in the perimenopausal phase may experience irregular ovulation due to ovarian dysfunction, leading to an inability to ovulate on a regular schedule.
As a result, the endometrium continues to proliferate and thicken under the influence of pre-ovulatory female hormones, causing irregular menstrual periods and occasionally heavy menstrual bleeding resembling a hemorrhage.
However, when there is persistent endometrial hyperplasia and frequent abnormal uterine bleeding, it is crucial to arrange for a pathological examination through endometrial curettage to rule out the possibility of endometrial neoplasia.

Reply Date: 2011/06/19

More Info


Understanding thickened endometrium and heavy menstrual bleeding is crucial, especially for women approaching perimenopause or menopause. The symptoms you describe—irregular menstrual cycles, heavy bleeding, and the need for medical intervention—are common in women around your age, particularly as they approach the transition into menopause.

The endometrium, or the lining of the uterus, undergoes cyclical changes influenced by hormonal fluctuations throughout a woman's reproductive years. In the perimenopausal phase, which typically occurs in women in their 40s, hormonal imbalances can lead to irregularities in the menstrual cycle. This can manifest as prolonged bleeding, heavy menstrual flow, or even spotting between periods. The thickening of the endometrium is often a result of prolonged estrogen exposure without adequate progesterone to counterbalance it. This can lead to conditions such as endometrial hyperplasia, which is a precursor to more serious conditions, including endometrial cancer.

Your history of heavy menstrual bleeding and the need for a dilation and curettage (D&C) procedure indicates that your body has been struggling to regulate these hormonal changes effectively. The D&C can help remove excess endometrial tissue, which may alleviate some of the heavy bleeding. However, it is essential to understand that while this procedure can provide temporary relief, it does not address the underlying hormonal imbalance.

The use of progestins (like the yellow hormone you mentioned) and birth control pills is a common approach to manage heavy menstrual bleeding and thickened endometrium. These medications work by regulating the menstrual cycle and thinning the endometrial lining, which can help reduce bleeding. However, if you find that these treatments are not effective or if your symptoms persist, further evaluation may be necessary.

Regarding your concern about whether this is a sign of impending menopause, it is indeed possible. The transition to menopause can begin several years before the last menstrual period, and during this time, women may experience a variety of symptoms, including irregular periods, hot flashes, night sweats, and mood changes. The hormonal fluctuations can lead to the symptoms you are experiencing, including heavy bleeding and endometrial thickening.

It is also important to monitor your hemoglobin levels, especially since you mentioned experiencing anemia due to heavy menstrual bleeding. Iron supplementation is often necessary in such cases, but it is crucial to address the root cause of the bleeding to prevent further complications.

In summary, the symptoms you are experiencing are consistent with the changes that occur during perimenopause. It is essential to maintain regular follow-ups with your healthcare provider to monitor your endometrial health and manage your symptoms effectively. If heavy bleeding continues or worsens, further diagnostic procedures, such as a hysteroscopy or additional imaging, may be warranted to rule out any serious conditions. Always discuss any new symptoms or concerns with your healthcare provider to ensure appropriate management and care.

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