Impact of Sita's Lymecycline on Pregnancy: What You Need to Know - Obstetrics and Gynecology

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Hello Doctor, last month I took a medication to delay my period (Sita, also known as Medroxyprogesterone) because I was going abroad.
Before taking the medication, I confirmed that I was not pregnant.
However, after stopping the medication on September 24 (I took it from September 21 to September 24), I still hadn't gotten my period by October 6, so I went to a clinic for a pregnancy test.
The doctor informed me that I am pregnant and mentioned that the medication I took could affect the fetus.
My question is, does Sita really affect the fetus, and is it not advisable to continue the pregnancy? P.S.
My last menstrual period started on August 27.

Nono, 30~39 year old female. Ask Date: 2011/10/06

Dr. Lü Lizheng reply Obstetrics and Gynecology


Dear Nono: Hello, the ingredients in general contraceptive medications are just hormones, and they do not have much impact on early embryos, so there is no need to worry.
Moreover, during the time you are taking the medication, the fertilized egg has just implanted and is still just a mass of cells, which has not yet begun to differentiate, so it is not yet at a stage where it can be affected by the medication.
Wishing you peace and health.
Sincerely, Dr.
Li-Cheng Lu, Director of the Department of Obstetrics and Gynecology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2011/10/06

More Info


When considering the impact of Lymecycline (known as Sita) on pregnancy, it is essential to understand the classification of this medication and its potential effects on fetal development. Lymecycline is a tetracycline antibiotic, which is generally classified as Category D by the FDA. This classification indicates that there is evidence of risk to the human fetus based on human data, but the benefits of the drug may outweigh the risks in certain situations.

Tetracyclines, including Lymecycline, are known to affect bone and tooth development in fetuses and young children. They can lead to permanent discoloration of teeth and may also impact bone growth. This is particularly concerning during the second and third trimesters of pregnancy when fetal bones are developing rapidly. The use of tetracyclines during pregnancy is generally discouraged unless absolutely necessary, as the potential risks to the developing fetus can be significant.

In your case, since you took Lymecycline for a short period before discovering your pregnancy, it is crucial to consult with your healthcare provider. They can assess the duration of exposure and any potential risks based on your specific situation. It is also important to consider the timing of your medication in relation to your pregnancy. Since you stopped taking the medication on September 24 and confirmed your pregnancy on October 6, the exposure was limited to a few days, which may mitigate some risks. However, the effects of any medication can vary depending on individual circumstances, including the dosage and the timing of exposure during critical periods of fetal development.

Regarding your concern about whether to continue with the pregnancy, it is essential to have an open discussion with your healthcare provider. They can provide you with personalized advice based on your medical history, the specifics of your medication use, and the current health of your pregnancy. In many cases, the presence of a medication in the early stages of pregnancy does not necessarily mean that there will be adverse effects on the fetus, especially if the exposure was brief.

In addition to discussing the potential impacts of Lymecycline, your healthcare provider may recommend additional monitoring or tests, such as ultrasounds or genetic counseling, to ensure that the pregnancy is progressing healthily. They can also provide guidance on prenatal care and any necessary precautions you should take moving forward.

In summary, while Lymecycline is associated with potential risks during pregnancy, the short duration of your exposure may lessen those risks. It is crucial to consult with your healthcare provider to assess your specific situation and to receive tailored advice on how to proceed with your pregnancy. They will be able to provide the most accurate information and support based on the latest medical guidelines and your individual health needs.

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