Abnormal Blood Test Results: Could It Be Thalassemia? - Cardiology

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Could you please clarify what specific information you are seeking regarding blood tests?


Hello Doctor: A few days ago, I went to the hospital for a pre-pregnancy check-up, and after receiving the report, it showed that my average red blood cell volume had abnormal values as follows: WBC 9.42, RBC 5.51 (H) - abnormal, HGB 11.9, HCT 34.7, MCV 63.0 (L) - abnormal, MCH 21.6 (L) - abnormal, MCHC 34.3, RDW-CV 15.8, RDW-SD 35.9, Platelet 312.
I would like to ask if this could possibly indicate thalassemia? What dietary and lifestyle considerations should I keep in mind regarding the abnormal results? I have recently been taking iron supplements and folic acid; could this have any impact? Thank you for your explanation.
^_^

^_^, 30~39 year old female. Ask Date: 2011/11/07

Dr. He Dongjin reply Cardiology


Hello, this is microcytic anemia, which may be due to iron deficiency anemia, so taking iron supplements is fine.
As for folic acid, it is associated with macrocytic anemia, so currently taking folic acid does not help.
Red meat, raisins, and spinach can be beneficial.
Changhua Hospital cares about you.

Reply Date: 2011/11/07

More Info


Based on the blood test results you've provided, it appears that there are several abnormal values that warrant further investigation, particularly concerning the possibility of thalassemia or other forms of microcytic anemia.

Understanding Your Blood Test Results
1. Red Blood Cell (RBC) Count: Your RBC count is slightly elevated at 5.51, which can sometimes occur in response to chronic hypoxia or other compensatory mechanisms.


2. Hemoglobin (HGB): At 11.9 g/dL, your hemoglobin is on the lower side of normal, indicating that you may be experiencing mild anemia.

3. Hematocrit (HCT): A hematocrit of 34.7% is also within the lower range, which aligns with the presence of anemia.

4. Mean Corpuscular Volume (MCV): The MCV of 63.0 fL is notably low, indicating microcytic red blood cells. This is a key indicator often associated with thalassemia or iron deficiency anemia.

5. Mean Corpuscular Hemoglobin (MCH): Your MCH is also low at 21.6 pg, which further supports the presence of microcytic anemia.

6. Mean Corpuscular Hemoglobin Concentration (MCHC): The MCHC is normal at 34.3 g/dL, which suggests that the red blood cells, while small, are adequately saturated with hemoglobin.

7. Red Cell Distribution Width (RDW): The RDW values (15.8 and 35.9) indicate a variation in red blood cell size, which can be seen in conditions like thalassemia or iron deficiency anemia.

8. White Blood Cell (WBC) Count and Platelet Count: Both are within normal ranges, which is a good sign as it suggests that the bone marrow is functioning adequately in producing these cells.


Could It Be Thalassemia?
Given the low MCV and MCH values, thalassemia is a strong consideration. Thalassemia is a genetic blood disorder characterized by reduced hemoglobin production, leading to microcytic anemia. The presence of low MCV and MCH, along with normal iron studies (if they were performed), would support this diagnosis.


Dietary and Lifestyle Considerations
If thalassemia is confirmed, dietary management is essential. Here are some recommendations:
1. Iron Intake: Since you are currently taking iron supplements, it's crucial to monitor your iron levels. In thalassemia, excessive iron can accumulate in the body, leading to complications. Therefore, consult your healthcare provider about the necessity of continuing iron supplementation.

2. Folic Acid: Continue taking folic acid, as it is vital for red blood cell production. Foods rich in folate include leafy greens, legumes, and fortified cereals.

3. Balanced Diet: Focus on a balanced diet rich in vitamins and minerals. Include foods high in vitamin B12 (like meat, dairy, and eggs) and vitamin C (citrus fruits, bell peppers) to enhance iron absorption.

4. Avoid Iron-Rich Foods: If thalassemia is confirmed, you may need to limit foods high in iron, such as red meat and iron-fortified cereals, unless advised otherwise by your doctor.

5. Regular Monitoring: Regular follow-ups with your healthcare provider are essential to monitor your blood counts and adjust your treatment plan as necessary.


Conclusion
In summary, your blood test results suggest the possibility of thalassemia, particularly due to the low MCV and MCH values. It is essential to discuss these results with your healthcare provider, who may recommend further testing, such as hemoglobin electrophoresis, to confirm the diagnosis. Additionally, dietary adjustments and regular monitoring will be crucial in managing your condition effectively. Always consult your healthcare provider before making any changes to your medication or diet.

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