Normal Tension Glaucoma: Causes and Symptoms Explained - Ophthalmology

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About glaucoma?


Yes, the term "Normal Tension Glaucoma (NTG)" does exist.
It refers to a type of glaucoma where optic nerve damage occurs despite the intraocular pressure being within the normal range.
The exact cause of NTG is not fully understood, but it is believed that factors such as reduced blood flow to the optic nerve, genetic predisposition, and other systemic conditions may contribute to the development of this condition.
Regarding the perception of flashes of light or unexplained spots in the vision, this phenomenon is often associated with a condition known as "photopsia." It can occur due to various reasons, including retinal detachment, vitreous detachment, or other retinal issues.
It is important to consult an eye care professional if you experience these symptoms, as they may indicate a serious underlying condition that requires evaluation and treatment.

Jia, 10~19 year old female. Ask Date: 2011/12/03

Dr. Qiu Hanqing reply Ophthalmology


Hello! 1) Glaucoma refers to a group of diseases that cause "optic nerve damage" and lead to "visual function abnormalities," with elevated intraocular pressure being just one of the risk factors.
2) Normal-tension glaucoma (also known as low-tension glaucoma) is a subtype of open-angle glaucoma, characterized by the presence of optic nerve damage and visual function abnormalities despite intraocular pressure remaining within the generally accepted normal range.
The causes of normal-tension glaucoma, aside from genetic factors, are related to conditions that result in insufficient blood flow to the optic nerve.
3) The perception of lightning-like flashes or unexplained light spots in the eyes has many differential diagnoses.
In addition to diseases of the retina and optic nerve, there are also central nervous system disorders that must be thoroughly evaluated through detailed medical history and relevant examinations for accurate diagnosis.
Wishing you safety.

Reply Date: 2011/12/03

More Info


Yes, the term "Normal Tension Glaucoma" (NTG) is indeed a recognized condition in the field of ophthalmology. Unlike typical glaucoma, which is characterized by elevated intraocular pressure (IOP), NTG occurs in patients who have normal IOP levels, typically defined as less than 21 mmHg. This condition can be perplexing because it challenges the conventional understanding that high eye pressure is the primary risk factor for glaucoma.
The exact causes of NTG are not fully understood, but several factors may contribute to its development. One significant factor is the susceptibility of the optic nerve to damage, which can occur even at normal pressure levels. This susceptibility may be influenced by various factors, including:
1. Vascular Factors: Insufficient blood flow to the optic nerve can lead to damage. Conditions that affect blood circulation, such as systemic hypotension or vasospasm, may play a role in NTG.

2. Optic Nerve Vulnerability: Some individuals may have an inherently more vulnerable optic nerve, which can be damaged by lower levels of pressure than what would typically cause harm in others.

3. Genetic Factors: There may be a hereditary component to NTG, as it can run in families.

4. Other Medical Conditions: Conditions such as migraines, sleep apnea, and systemic diseases may also increase the risk of developing NTG.

Symptoms of NTG can be similar to those of other types of glaucoma, including peripheral vision loss, which may progress unnoticed until significant damage has occurred. Patients may not experience any symptoms until the disease has advanced, making regular eye examinations crucial for early detection.

Regarding the visual disturbances you mentioned, such as seeing flashes of light or unexplained spots, these symptoms can be associated with various ocular conditions. Flashes of light, often described as "photopsia," can occur due to:
1. Vitreous Detachment: As we age, the vitreous gel in the eye can shrink and pull away from the retina, causing flashes of light.

2. Retinal Issues: Conditions such as retinal tears or detachments can also cause similar visual phenomena and require immediate medical attention.

3. Migraine Aura: Some individuals experience visual disturbances, including flashes or zigzag patterns, as part of a migraine aura, even without a headache.

4. Other Ocular Conditions: Conditions like posterior uveitis or inflammation of the retina can also lead to visual disturbances.

If you are experiencing these symptoms, it is essential to consult with an eye care professional for a comprehensive evaluation. They may recommend tests such as optical coherence tomography (OCT), visual field testing, or a thorough examination of the retina to rule out any serious underlying conditions.

In summary, Normal Tension Glaucoma is a legitimate condition characterized by optic nerve damage at normal IOP levels, and it underscores the importance of regular eye examinations, especially for individuals with risk factors. If you are experiencing unusual visual symptoms, seeking prompt medical attention is crucial to ensure proper diagnosis and management.

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