Can Topical Treatments Remove Skin Lesions Before Surgery? - Dermatology

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For skin lesions that require surgical intervention, is it possible to apply medication to make the pigmented lesions disappear?

123, 20~29 year old female. Ask Date: 2001/08/18

Dr. Zheng Lizhen reply Dermatology


To determine the most appropriate treatment method, it is essential to identify the specific type of pigmentation disorder.

Reply Date: 2001/08/18

More Info


When it comes to skin lesions, particularly pigmented lesions that may require surgical intervention, topical treatments can play a role in managing the condition, but they are not a guaranteed solution for complete removal. The effectiveness of topical treatments largely depends on the type of skin lesion, its characteristics, and the underlying cause.

Topical treatments, such as those containing retinoids (like tretinoin), hydroquinone, or other skin-lightening agents, can help in reducing the appearance of certain types of pigmented lesions, such as age spots or melasma. These treatments work by promoting skin cell turnover, inhibiting melanin production, and improving overall skin texture. However, they may not be effective for all types of lesions, especially those that are deeper or more complex, such as seborrheic keratosis, moles, or other nevi.

In cases where the lesion is suspected to be more serious, such as a potential melanoma or other skin cancers, it is crucial to consult a dermatologist for a thorough evaluation. In such instances, topical treatments may not only be ineffective but could also delay necessary surgical intervention. If a lesion is determined to be benign and not requiring immediate surgical removal, topical treatments may be used as a complementary approach to improve the skin's appearance.

It is also important to note that while some topical treatments can help lighten pigmentation, they may not completely eliminate the lesion. For instance, if the lesion is raised or has a significant texture difference compared to the surrounding skin, surgical excision may still be the most effective option. Additionally, there is a risk that some topical treatments could irritate the skin or cause adverse reactions, especially if used improperly or on sensitive areas.

In summary, while topical treatments can assist in managing certain skin lesions and may improve their appearance, they are not a substitute for surgical removal when indicated. If you are considering using topical treatments for a pigmented lesion, it is advisable to discuss this with a dermatologist who can provide personalized recommendations based on your specific condition. They can help determine the best course of action, whether that involves topical treatments, monitoring the lesion, or proceeding with surgical options.

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