Elevated Leukocytes in Urine Tests: Kidney Health Concerns - Urology

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Urinalysis inquiries?


Hello, doctor.
I would like to ask about my mother's health check-up at the end of October.
In the urine test, two items were flagged in red: leukocytes with a result of {3+} and WBC in urine with a count of {10-20}, both of which are elevated.
Does this indicate a problem with her kidneys? Last year, the only abnormal finding was a slightly elevated uric acid level of 6.8.
A friend suggested that she drink lemon vinegar to lower uric acid.
This year, her uric acid level has decreased to a normal level of 5.7, but now these two urine test items are elevated.
I am worried that there might be an issue with her kidneys.

A Min, 50~59 year old female. Ask Date: 2011/12/28

Dr. Li Yilun reply Urology


Hello, the white blood cell count and the presence of white blood cells in urine both indicate an inflammatory response in the urine.
Therefore, this report shows that there is inflammation in the urine.
However, treatment should depend on whether the patient has any uncomfortable symptoms.
Inflammation is often associated with symptoms such as frequent urination, painful urination, and a burning sensation.
If symptoms are present, it is advisable to seek treatment at a medical facility.
If there are no symptoms, it is recommended to drink plenty of water.
If necessary, the patient can also return to the hospital for re-evaluation at any time.

Reply Date: 2011/12/28

More Info


Elevated leukocytes in urine tests can indeed raise concerns regarding kidney health, and it is important to interpret these results in the context of your mother's overall health and any accompanying symptoms. The presence of leukocytes, or white blood cells (WBCs), in urine can indicate inflammation or infection in the urinary tract, which may involve the kidneys, bladder, or urethra.

In your mother's case, the urine test results show leukocytes at a level of 3+ and WBCs between 10-20, which are both considered elevated. This could suggest a urinary tract infection (UTI) or possibly a more serious condition affecting the kidneys, such as pyelonephritis (a kidney infection). It is important to note that elevated leukocytes alone do not definitively indicate kidney disease; they are often a sign of infection or inflammation.

Given that your mother had a previous health check where her uric acid levels were slightly elevated but have since normalized, it is reassuring that her uric acid levels are now within the normal range. However, the new findings of elevated leukocytes in her urine warrant further investigation. It is crucial to consider whether she has experienced any symptoms such as fever, chills, flank pain, or changes in urinary habits (e.g., increased frequency, urgency, or painful urination), as these could provide additional context for her current condition.

To further evaluate her kidney health, the following steps are recommended:
1. Follow-Up Testing: A repeat urine test may be necessary to confirm the presence of leukocytes and to check for other abnormalities, such as the presence of nitrites (which can indicate a bacterial infection) or the presence of protein (which can indicate kidney damage).

2. Urine Culture: If a UTI is suspected, a urine culture can help identify the specific bacteria causing the infection and determine the appropriate antibiotic treatment.

3. Imaging Studies: If there is a concern for kidney involvement, imaging studies such as an ultrasound may be warranted to assess the kidneys for any structural abnormalities or signs of infection.

4. Consultation with a Specialist: If the elevated leukocytes persist or if there are any concerning symptoms, it may be beneficial for your mother to consult a nephrologist (kidney specialist) for a more comprehensive evaluation.

5. Monitoring and Lifestyle Adjustments: Encourage your mother to stay well-hydrated, as adequate fluid intake can help flush out the urinary system. Additionally, maintaining a balanced diet and managing any other health conditions (such as hypertension or diabetes, if applicable) can support overall kidney health.

In summary, while elevated leukocytes in urine tests can indicate potential kidney issues, they are more commonly associated with infections. It is essential to conduct further evaluations to determine the underlying cause and to ensure that appropriate treatment is initiated if necessary. Your mother's health care provider will be able to guide her through the next steps based on her specific situation and test results.

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