Calluses in Children: When to Consider a Skin Biopsy? - Dermatology

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Should a callus be biopsied for examination?


Hello Dr.
Wu, I apologize for bothering you.
I would like to ask you some questions.
Thank you.
My son is currently over 4 years old, and he has developed severe calluses on the inner side of his left foot (this condition started to appear gradually when he began walking like a crab and has progressively worsened, extending in a straight line from his big toe to his heel).
From ages 2 to 3, we initially took him to a dermatologist for keratolytic treatment to soften the calluses, but the calluses returned after treatment.
Later, we consulted a rehabilitation specialist, and X-rays showed no skeletal issues.
It seems that the pressure he exerts is predominantly on his left foot, which may be the reason for the severe callus formation.
He has also been wearing corrective insoles for over a year, which seems to have provided slight improvement, but the callus issue remains severe.
Yesterday, we took him to a dermatology clinic again, and the doctor suggested it might be "plantar keratoderma." To confirm this, a biopsy at a major hospital would be necessary, which is quite concerning for me! Is it appropriate for a child over 4 years old to undergo this biopsy? I am worried about the potential side effects of local anesthesia, but I am also concerned about whether the severe calluses could have further implications.
I wonder what preliminary tests are needed before the biopsy? Blood tests? Urinalysis? What are the risks and side effects of local anesthesia? Will there be pain during the biopsy? Will there be pain after the anesthesia wears off? How should the wound be cared for? As a mother, I am truly worried, and I wonder if Dr.
Wu could provide some advice! I would be very grateful.
Wishing you good health and happiness!

pinggu, 20~29 year old female. Ask Date: 2012/03/18

Dr. Wu Yuxin reply Dermatology


Hello: Based on your description, the likelihood of developing calluses due to pressure in children aged 2-4 years is quite rare.
Congenital palmoplantar keratoderma is predominantly bilateral, but it can initially present unilaterally.
A biopsy is indeed necessary; it typically requires local anesthesia (injection of anesthetic), but the patient remains awake, which may be challenging for a 4-year-old child.
It might be necessary to sedate the child.
As long as the child remains still, the procedure can be completed within 20 minutes, and the wound may require about two stitches.
Generally, the stitches can be removed after a week, as the procedure only involves the skin and does not affect deeper tissues, so there should not be any significant long-term complications.
I'm not sure where you are located, but I recommend going to a medical center for evaluation, such as Taichung Veterans General Hospital or China Medical University Hospital if you are in Taichung City.
You can also search for images of palmoplantar keratoderma on Google for reference.

Reply Date: 2012/03/18

More Info


When it comes to understanding calluses in children, particularly in your son's case, it’s essential to consider various factors before deciding on a skin biopsy. Calluses, or thickened areas of skin, often develop as a protective response to repeated friction or pressure. In your son's situation, the calluses on the inner side of his left foot have likely formed due to the way he walks or plays, especially if he has a tendency to put more weight on that foot.


Understanding Calluses and Their Causes
Calluses are common in children, especially those who are active and engage in physical activities that put pressure on certain areas of their feet. In your son's case, the development of calluses from the big toe to the heel suggests a consistent pattern of pressure or friction. This can be exacerbated by improper footwear, such as shoes that do not fit well or do not provide adequate support.

Treatment Options
You mentioned that your son has undergone treatments such as softening the calluses and using corrective insoles. These are appropriate initial steps. However, if the calluses continue to recur despite these interventions, it may indicate an underlying issue that needs further investigation.

When to Consider a Skin Biopsy
A skin biopsy is typically considered when there is uncertainty about the diagnosis or if there is a suspicion of a more serious condition, such as a skin disorder like keratoderma or other dermatological issues. In your son's case, the dermatologist suggested the possibility of "palmar-plantar keratoderma," which could warrant further investigation through a biopsy.

1. Age and Suitability: While a biopsy can be performed on children, it is essential to weigh the risks and benefits. At 4 years old, your son is at an age where he can understand some aspects of the procedure, but it may still be challenging for him emotionally.

2. Risks of Local Anesthesia: Local anesthesia is generally safe, but like any medical procedure, it carries some risks. Potential side effects can include allergic reactions, temporary numbness, or swelling at the injection site. The pain associated with the biopsy itself is usually minimal due to the anesthesia, but as it wears off, your son may experience some discomfort.
3. Post-Procedure Care: After the biopsy, proper wound care is crucial to prevent infection and promote healing. This typically involves keeping the area clean and dry, applying any prescribed ointments, and monitoring for signs of infection, such as increased redness, swelling, or discharge.


Alternative Considerations
Before proceeding with a biopsy, it might be worthwhile to explore other options. For instance, a second opinion from another dermatologist could provide additional insights. Furthermore, if the calluses are primarily due to mechanical factors, addressing footwear and gait issues might be sufficient to alleviate the problem without the need for invasive procedures.


Conclusion
In summary, while a skin biopsy can provide valuable information, it is essential to consider your son's overall health, the potential risks involved, and whether less invasive options have been fully explored. Consulting with a pediatric dermatologist who specializes in children's skin conditions may also help clarify the best course of action. Your concerns as a parent are completely valid, and ensuring your child’s comfort and well-being should always be the priority.

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