Questions about liver ultrasound examination?
Hello, ultrasound physician: Last week, I underwent a routine ultrasound follow-up for gallbladder polyps.
The polyps have been monitored for 7 years and have consistently measured between 0.4 cm and 0.6 cm (the doctor said this is within the normal range of variation).
However, the physician (who is not a hepatobiliary or gastroenterology specialist) mentioned that my liver appears slightly coarse.
They also stated that this is a natural phenomenon of aging and not a cause for concern.
Should I really not worry? I'm quite anxious about this; how could this happen when my company health check a year ago reported no issues? I have always known that I do not have hepatitis B or C, and my liver function tests have consistently been between 15 and 25, which are normal.
For insurance purposes, I had blood tests for hepatitis B and C again, and the results were still negative (with positive hepatitis B antibodies).
My GOT was 17 and GPT was 19; the lab technician even remarked that my results were excellent and praised me for having a healthy liver.
I do not drink alcohol or smoke, and my lifestyle is relatively normal.
I am perplexed about whether there is an issue with my liver.
Over two years ago, I was prescribed antihistamines (Zyrtec) by a dermatologist for physical urticaria, and I have been taking them long-term.
The doctor mentioned that this medication has minimal side effects and can be taken long-term; I have reduced my dosage to one pill every three days over the past year.
Could my long-term use of antihistamines be causing drug-induced hepatitis? (But my GPT levels are normal.) I am very worried; how can I protect my liver?
Liu Xiaojie, 40~49 year old female. Ask Date: 2012/03/19
Dr. Chen Shidian reply Gastroenterology and Hepatology
Hello, Ms.
Liu.
The interpretation of ultrasound is quite subjective.
Most physicians tend to be conservative and may describe some findings as coarse echogenicity (fibrosis).
This can sometimes cause anxiety for patients.
Generally, as long as liver function remains normal over time and you are negative for hepatitis B and C, there is no cause for concern.
If you are still worried, you can consider a specialized ultrasound examination for liver fibrosis at Chang Gung Memorial Hospital in Kaohsiung, which is self-paid and costs around 1,000 to 2,000 NTD.
However, I believe that there is currently no necessity for this.
The staff at Changhua Hospital cares about your health.
Dr.
Chen Shih-Tien.
Reply Date: 2012/03/19
More Info
Understanding liver ultrasound results can be quite daunting, especially when you receive mixed messages from different healthcare providers. Based on your description, it seems that your ultrasound indicated a slightly coarse liver texture, which has raised concerns for you. Let's break down what this means and how it relates to your overall liver health.
What Does "Coarse Liver Texture" Mean?
A coarse liver texture on an ultrasound typically suggests that there may be some degree of liver disease or damage. However, it is essential to understand that "coarse" does not automatically indicate severe liver disease. It can be a sign of fatty liver disease, chronic liver disease, or even just a normal variant in some individuals. Given that your liver function tests (GOT and GPT) are within normal ranges, this is a positive sign. Normal liver function tests generally indicate that your liver is functioning well, despite the ultrasound findings.
Age and Liver Changes
As you mentioned, the physician suggested that the coarse texture could be a natural aging phenomenon. Indeed, as people age, their liver may undergo changes that can be reflected in imaging studies. These changes can include variations in texture and size, which may not necessarily correlate with liver function. Your physician's reassurance that this is not a cause for concern is valid, especially in the context of your normal liver function tests and absence of viral hepatitis.
Medication and Liver Health
You raised a concern about the long-term use of antihistamines and whether they could contribute to liver issues. Generally, most antihistamines, including the one you mentioned (likely cetirizine or a similar drug), are considered safe for long-term use and are not commonly associated with liver damage. Your normal liver enzyme levels further support that your liver is not adversely affected by this medication.
Monitoring and Follow-Up
Given that you have been monitoring a gallbladder polyp for several years without significant changes, it seems that your healthcare providers are taking a cautious but appropriate approach. Regular follow-ups are essential, especially for any abnormalities noted in imaging studies.
Recommendations for Liver Health
1. Maintain a Healthy Lifestyle: Continue your current lifestyle choices, including a balanced diet, regular exercise, and avoiding alcohol and smoking. These factors significantly contribute to liver health.
2. Regular Check-Ups: Keep up with your routine health screenings, including liver function tests and ultrasound evaluations as recommended by your healthcare provider.
3. Stay Informed: If you have concerns about your liver health or the implications of your ultrasound findings, do not hesitate to seek a second opinion, preferably from a hepatologist or a gastroenterologist specializing in liver diseases.
4. Monitor Symptoms: Be vigilant about any new symptoms, such as jaundice (yellowing of the skin or eyes), unexplained fatigue, or abdominal pain, and report these to your healthcare provider promptly.
5. Discuss Medications: If you have concerns about any medications you are taking, including over-the-counter drugs, discuss these with your doctor. They can provide guidance on any potential risks and benefits.
Conclusion
In summary, while the ultrasound findings may seem concerning at first glance, your normal liver function tests and the physician's reassurance suggest that there is no immediate cause for alarm. Continue to monitor your health, maintain a healthy lifestyle, and keep open communication with your healthcare providers. If you remain anxious about your liver health, consider discussing your concerns with a specialist who can provide more tailored advice and reassurance.
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