the 4-Valent HPV Vaccine: Efficacy and Eligibility for Women

Quadrivalent HPV vaccine

Hello, doctor.
I would like to inquire about the quadrivalent HPV vaccine: 1- I am 37 years old and have no sexual experience.
Am I suitable for this vaccine? (The clinical trials only included participants up to 26 years old, so I'm unsure about the effectiveness for those over 30.) 2- What is the efficacy rate? 3- How long does the efficacy (protection) last? 4- How does your clinic price the vaccine? Thank you for your clarification.

nico yeh, 30~39 year old female. Ask Date: 2012/05/05

Dr. Lin Wenbin reply Obstetrics and Gynecology

Hello, 1.
Clinical trials only included participants up to 26 years of age because individuals without sexual experience (or those who have not been exposed to genital secretions from infected patients) generally show better efficacy.
Therefore, it is recommended to prioritize younger populations for vaccination.
However, there is no rule stating that individuals over 30 cannot receive the vaccine.
The age limit of 26 is merely a definition for the experimental group and not an absolute figure.
2.
For the prevention of cervical cancer, it is estimated that the vaccine is effective in about 60-70% of cases.
Actual data will require more time to assess differences as the vaccine is promoted.
3.
The protective efficacy varies among individuals, with an estimated prevention rate lasting 5 to 9 years.
4.
Since it is a self-paid medication, different hospitals may charge varying fees within a reasonable range.
For our hospital's pricing, it is necessary to inquire in person at the outpatient department, as it is not convenient to disclose on the website.

Reply Date: 2012/05/05

More Info

The 4-valent HPV vaccine, known as Gardasil, is designed to protect against four types of human papillomavirus (HPV): types 6, 11, 16, and 18. These types are associated with various conditions, including cervical cancer, genital warts, and other anogenital cancers. Your questions about the vaccine's efficacy, eligibility, and duration of protection are important, especially considering your age and sexual history.

1. Eligibility for the Vaccine at Age 37: While clinical trials for the HPV vaccine primarily focused on individuals under 26, there is no upper age limit for receiving the vaccine. The vaccine is most effective when administered before the onset of sexual activity, but it can still provide benefits for those who are older and have not been previously exposed to the HPV types covered by the vaccine. Since you mentioned that you have no sexual experience, you are likely to benefit from the vaccine, as it can help prevent future infections from the types it covers.

2. Efficacy Rate: The efficacy of the 4-valent HPV vaccine is estimated to be around 70% to 90% in preventing diseases caused by the HPV types it targets, particularly cervical cancer and genital warts. The vaccine is most effective when given before any exposure to the virus, which is why vaccination is recommended at a younger age. However, even if you are older, the vaccine can still provide significant protection against the types of HPV it covers, especially if you have not been previously infected.

3. Duration of Protection: Studies suggest that the protective effects of the HPV vaccine can last for at least 5 to 9 years, with some evidence indicating that immunity may persist even longer. Ongoing research continues to evaluate the long-term effectiveness of the vaccine, and booster doses are not currently recommended for those who have completed the vaccination series. However, the long-term benefits of vaccination, particularly in preventing cervical cancer, are well-documented.

4. Cost of the Vaccine: The cost of the HPV vaccine can vary depending on the healthcare provider and insurance coverage. In the United States, the price for the complete series of the 4-valent HPV vaccine can range from $400 to $600, but many insurance plans cover the vaccine, especially for individuals under 26. It is advisable to check with your healthcare provider or insurance company for specific pricing and coverage details.

In summary, the 4-valent HPV vaccine is a valuable preventive measure against certain types of HPV, even for individuals over 26 and those with no sexual experience. Its efficacy is significant, and it can provide long-lasting protection. If you are considering vaccination, it is advisable to consult with your healthcare provider to discuss your specific circumstances and any potential benefits of receiving the vaccine. They can provide personalized recommendations based on your health history and current guidelines.

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Hello, the examination results are all normal, and there should be no warts. Don't worry. Wishing you good health.