Why Your Mole May Regrow and Itch: Skin Concerns - Dermatology

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The mole has been excised but has grown back and is itchy?


Hello Doctor, I previously had a mole on my thigh removed, and the biopsy results were benign.
Three months later, it has grown back in an asymmetrical shape, and a small mole has also started to develop at the edge of the incision where there was no mole before.
The entire incision area occasionally itches.
From my online research, I found that asymmetrical moles could be due to incomplete removal during the initial procedure, which might explain the irregular shape.
However, the itching concerns me.
Could you clarify whether the itching refers to the entire incision area or just the mole itself? Given my situation, do I need to undergo another excision, and would a second excision pose a risk of malignant transformation of the mole? Thank you for taking the time to respond, Doctor.

Netsw, 20~29 year old female. Ask Date: 2012/05/10

Dr. Lin Xinpeng reply Dermatology


Hello: The reason why a mole may grow back after excision is often due to the presence of residual mole cells that were not completely removed during the initial procedure.
This can lead to reactive hyperplasia due to irritation from the incision, resulting in localized inflammation and itching.
Alternatively, the initially excised mole may not have included the pathological portion, which can then proliferate into irregular lesions.
Itching itself is not necessarily a precursor to malignancy; rather, you should be concerned if there is rapid proliferation, ulceration, or changes in color of the lesion.
It is advisable to return to the clinic for a second excision and biopsy to rule out any potential malignancy.

Reply Date: 2012/05/10

More Info


When it comes to skin concerns, particularly regarding moles, it is essential to understand the underlying factors that may contribute to their regrowth and associated symptoms such as itching. In your case, having previously excised a mole from your thigh that was later found to be benign, only to see it regrow in an asymmetrical manner, raises several important considerations.

Firstly, the regrowth of a mole can occur for various reasons. One possibility is that the initial excision did not remove the entire mole, including its roots. This incomplete removal can lead to the mole reappearing in a different shape or size. The asymmetry you are observing could be a sign that the mole is not developing normally, which is often a characteristic of atypical moles that may warrant further investigation.

The itching you are experiencing can be attributed to several factors. It could be a reaction to the healing process of the skin following the initial excision. Itching is a common symptom during the healing phase as the skin regenerates and new cells form. However, if the itching persists or is accompanied by changes in the mole's appearance, it could indicate irritation or even a potential issue with the mole itself.

In terms of whether the itching is localized to the mole or the surrounding area, it is crucial to pay attention to the specific sensations. If the itchiness is primarily around the excision site and not directly on the mole, it may simply be a part of the healing process. However, if the mole itself is itchy, this could be a sign of irritation or a change in the mole's characteristics, which should be evaluated by a healthcare professional.

Regarding your concern about needing another excision, it is advisable to consult with a dermatologist. They can perform a thorough examination of the mole and the surrounding skin to determine if further intervention is necessary. If the mole shows signs of atypical features, such as irregular borders, varied colors, or changes in size, a biopsy may be recommended to rule out any potential malignancy.

As for the risk of causing changes to the mole during a second excision, it is essential to understand that any surgical procedure carries some risk. However, a skilled dermatologist will take precautions to minimize these risks and ensure that the procedure is performed safely. They will also provide you with information on what to expect during the healing process and how to care for the area post-surgery.

In summary, it is crucial to monitor any changes in your skin, especially concerning moles. If you notice asymmetry, changes in color, or persistent itching, seeking the advice of a dermatologist is the best course of action. They can provide a comprehensive evaluation and determine the appropriate steps to take, ensuring your skin health is prioritized. Regular skin checks and being aware of any changes in your moles can help in early detection of potential issues, leading to better outcomes.

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