Unidentified Liver Tumors: Risks and Insights for Patients - Gastroenterology and Hepatology

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A tumor of unclear origin on the surface of the liver?


Hello Dr.
Chen,
I would like to ask about my father (61 years old).
He recently underwent examinations and was diagnosed with fatty liver, and a 1.2 cm tumor was found on the surface of his liver.
However, both ultrasound and CT scans could not determine what it is.
His liver function tests and other examinations are normal.
In this situation, is the likelihood of it being benign higher? If it is benign, what could it possibly be? Lastly, I would like to ask about the discrepancy in measurements; the first ultrasound showed the tumor as 1 cm, but the subsequent CT scan showed it as 1.2 cm.
Is this kind of variation normal? Thank you for your response!

7, 60~69 year old female. Ask Date: 2012/05/23

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Hello: Based on the information above, there is a high possibility of a hepatic lipoma, hepatic cyst, or hepatic hemangioma.
These are likely benign tumors, as they are often not spherical, which may result in some discrepancies when measured from different angles.
It is recommended to follow up in 2 to 3 months and discuss with your physician.
Sincerely, Dr.
Chi-Feng Chen, Taoyuan Hospital, Department of Health.

Reply Date: 2012/05/23

More Info


When it comes to unidentified liver tumors, particularly in the context of a patient with a history of fatty liver, there are several important considerations to keep in mind. Your father's situation, where a 1.2 cm tumor was detected on imaging studies but remains undetermined in nature, raises valid concerns and questions regarding the potential risks and implications.

Firstly, the fact that your father's liver function tests are normal is a positive sign. Elevated liver enzymes (AST, ALT) often indicate liver inflammation or damage, which can be associated with more serious conditions, including malignancies. However, normal liver function tests do not rule out the possibility of a tumor, as some tumors can exist without causing immediate changes in liver function.

In terms of the likelihood of the tumor being benign, it is indeed possible. Benign liver tumors include hemangiomas, focal nodular hyperplasia (FNH), and hepatic adenomas. Hemangiomas are the most common benign tumors of the liver and are often asymptomatic. FNH is also typically asymptomatic and does not require treatment unless symptomatic. Hepatic adenomas, while benign, can have a risk of bleeding or transformation into malignancy, especially in patients who use oral contraceptives or have metabolic disorders.

Regarding the growth of the tumor from 1 cm to 1.2 cm, slight variations in measurements between ultrasound and CT scans can occur due to several factors, including the imaging technique, the operator's experience, and the inherent limitations of each modality. Ultrasound is operator-dependent and can sometimes underestimate or overestimate the size of lesions. CT scans, while generally more accurate, can also have discrepancies based on the timing of the scan and the contrast used. Therefore, a small increase in size is not unusual and should be interpreted in the context of clinical findings and follow-up imaging.

It is essential to monitor the tumor over time. If the tumor remains stable in size and your father's liver function remains normal, the likelihood of it being benign increases. However, if there are changes in size, symptoms develop, or liver function tests become abnormal, further evaluation may be warranted. This could include additional imaging studies, such as MRI, or even a biopsy if there is a strong suspicion of malignancy.

In summary, while the presence of a liver tumor can be concerning, the context of normal liver function tests and the small size of the tumor are encouraging signs. The possibility of it being benign is plausible, but ongoing monitoring and potentially further evaluation are crucial. It is advisable to maintain close communication with your healthcare provider to ensure that any changes in your father's condition are promptly addressed. Regular follow-up imaging and consultations with a hepatologist or oncologist may provide further clarity and peace of mind.

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