Can Fatty Liver and High Uric Acid Levels Be Reversed? - Gastroenterology and Hepatology

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Fatty liver and high uric acid?


Hello Dr.
Tsai,
I would like to consult you regarding issues related to fatty liver and uric acid.
Last month, my blood test results showed: 1.
SGPT 71 (reference range 4-44) 2.
Triglycerides 132 (50-130) 3.
Uric acid 11.6 (3.6-8).
These three values are elevated, while the rest are normal.
An abdominal ultrasound indicated fatty liver.
At that time, my height was 173 cm and my weight was 77 kg.
The doctor prescribed Sulfin 100 mg to be taken after breakfast, which I have been taking for a month, along with advice to drink plenty of water, exercise moderately, and reduce oil and salt intake.
Today, I weighed myself and found I am now 74 kg.
I have been following the dietary and medication advice as instructed.

I would like to ask Dr.
Tsai if it is possible for the values related to fatty liver and uric acid to return to normal or even improve completely? Thank you for taking the time to respond, Dr.
Tsai.
(I do not smoke or drink alcohol, but my previous diet was less restrictive and my exercise was limited.
Now, in addition to monitoring my diet, I have also started jogging.)

A Wei, 20~29 year old female. Ask Date: 2012/08/24

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: (1) Liver function in fatty liver disease may be normal or elevated, which is referred to as steatohepatitis.
Both fatty liver and steatohepatitis are reversible conditions.
However, prolonged steatohepatitis that does not resolve can eventually lead to cirrhosis, which is irreversible.
(2) Blood tests revealing elevated uric acid levels indicate hyperuricemia.
Prolonged hyperuricemia can lead to the accumulation of uric acid crystals in the joints, resulting in gouty arthritis.
Both hyperuricemia and gouty arthritis can be managed and controlled through medication or dietary changes.
However, once tophi (urate crystals) form in the joints, recovery becomes more challenging.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2012/08/24

More Info


Yes, both fatty liver disease and high uric acid levels can potentially be reversed or significantly improved through lifestyle modifications, including dietary changes and increased physical activity.

Fatty Liver Disease
Fatty liver disease, particularly non-alcoholic fatty liver disease (NAFLD), is characterized by the accumulation of fat in liver cells. It is often associated with obesity, insulin resistance, and metabolic syndrome. The good news is that fatty liver is generally considered a reversible condition, especially in its early stages.
1. Weight Loss: One of the most effective ways to improve fatty liver is through weight loss. Studies have shown that losing even 5-10% of body weight can lead to significant improvements in liver health. In your case, you have already lost some weight, which is a positive step. Continuing this trend can help reduce liver fat and improve liver enzyme levels.

2. Dietary Changes: A balanced diet low in saturated fats, refined carbohydrates, and sugars is crucial. Incorporating more fruits, vegetables, whole grains, and healthy fats (like those found in fish, nuts, and olive oil) can be beneficial. Reducing your intake of processed foods and sugars can help lower triglyceride levels and improve overall liver health.

3. Exercise: Regular physical activity is essential for managing fatty liver. Aim for at least 150 minutes of moderate-intensity aerobic exercise each week, combined with strength training exercises on two or more days a week. This can help improve insulin sensitivity and promote weight loss.

4. Monitoring and Follow-Up: Regular check-ups with your healthcare provider to monitor liver function tests and ultrasound findings are important. This will help assess the effectiveness of your lifestyle changes and make necessary adjustments.


High Uric Acid Levels
High uric acid levels, or hyperuricemia, can lead to gout and other health issues. Like fatty liver, high uric acid levels can often be managed through lifestyle changes.

1. Dietary Modifications: Reducing the intake of purine-rich foods (such as red meat, organ meats, and certain seafood) can help lower uric acid levels. Additionally, limiting alcohol consumption and sugary beverages is crucial, as these can contribute to increased uric acid production.

2. Hydration: Staying well-hydrated helps the kidneys flush out uric acid more effectively. Aim to drink plenty of water throughout the day.

3. Weight Management: Similar to fatty liver, losing weight can help lower uric acid levels. As you lose weight, your body may produce less uric acid, and your kidneys may become more efficient at excreting it.

4. Medication: In some cases, medications may be necessary to manage high uric acid levels, especially if dietary changes alone are insufficient. It’s important to follow your healthcare provider's recommendations regarding any prescribed medications.


Conclusion
In summary, both fatty liver disease and high uric acid levels can be improved with lifestyle changes. Your current efforts to eat healthier and exercise are on the right track. Continue to focus on maintaining a balanced diet, staying active, and monitoring your health with your physician. With dedication and consistency, it is possible to reverse these conditions and improve your overall health. Always consult with your healthcare provider before making significant changes to your diet or exercise routine, especially if you have existing health conditions.

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