Polycystic Ovary Syndrome: Symptoms, Treatments, and Management - Obstetrics and Gynecology

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Polycystic Ovary Syndrome (PCOS)


I am currently 167 cm tall and weigh 51.5 kg.
I started my menstruation at the age of 13 (October 1998).
From October to January 1999, my menstrual cycle was very irregular, and I did not have my period from January to October 1999.
After visiting the hospital for examination, it was found that I had elevated male hormones with an EIA of 0.78 ng/ml, while thyroid hormones and blood glucose levels were normal.
An ultrasound showed multiple follicles.
Since then, I have been taking medication to induce menstruation every six months.
In January 2012, I took traditional Chinese medicine, and my period came naturally.
However, in July, blood tests revealed insufficient female hormones: Prolactin 4.17 ng/ml, Estradiol 21.97 pg/ml, and EIA 0.21 ng/ml.
Question 1: How often should I take medication to induce menstruation? Is it appropriate every 2 months, 3 months, 4 months, or 6 months?
Question 2: A physician suggested taking blood sugar-lowering medication for treatment.
Is it better to take medication to induce menstruation or blood sugar-lowering medication? What are the side effects and risks associated with each?
Question 3: Does taking blood sugar-lowering medication increase the risk of developing diabetes?
Question 4: Do I truly have Polycystic Ovary Syndrome (PCOS)? Some doctors say I do, while others say it can only be diagnosed after the age of 18, or that a diagnosis can only be made three years after the onset of menstruation.
Question 5: Is this condition related to diet? How can I improve my situation? Please provide some advice.
Thank you!

Ni Ni, 10~19 year old female. Ask Date: 2012/08/29

Dr. Dong Yuhong reply Obstetrics and Gynecology


Hello; during adolescence, menstrual irregularities are more common.
Treatment should involve a comprehensive assessment that includes general ultrasound, hormonal evaluation, and physiological development.
You can discuss specific treatment plans further with your attending physician.
Thank you!

Reply Date: 2012/08/29

More Info


Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. It is characterized by a combination of symptoms that can include irregular menstrual cycles, excess androgen levels (which can lead to symptoms such as hirsutism or acne), and polycystic ovaries as seen on ultrasound. Given your detailed history and symptoms, it seems you are experiencing several classic signs of PCOS.


Symptoms of PCOS
1. Irregular Menstrual Cycles: Many women with PCOS experience infrequent or prolonged menstrual periods. In your case, you mentioned that your periods were irregular and sometimes absent, which is common in PCOS.

2. Excess Androgens: Elevated levels of male hormones can lead to symptoms such as acne, hirsutism (excessive hair growth), and scalp hair thinning. Your lab results indicated elevated male hormones, which aligns with this symptom.

3. Polycystic Ovaries: The presence of multiple small cysts on the ovaries is a hallmark of PCOS, which was confirmed by your ultrasound.


Treatment Options
1. Hormonal Treatments: Birth control pills are often prescribed to regulate menstrual cycles and reduce androgen levels. They can help manage symptoms like acne and hirsutism. If you are experiencing significant menstrual irregularities, a regimen of hormonal therapy may be beneficial.

2. Ovulation Induction: If you are trying to conceive, medications like Clomid (clomiphene citrate) can be used to induce ovulation. This is particularly useful for women with PCOS who have difficulty ovulating.

3. Metformin: This medication is commonly used to improve insulin sensitivity and can help with weight management and menstrual regularity in women with PCOS. It may also reduce the risk of developing type 2 diabetes, which is a concern for women with PCOS due to the associated insulin resistance.

4. Lifestyle Modifications: Weight management through diet and exercise is crucial. Even a modest weight loss of 5-10% can significantly improve symptoms and metabolic health. A balanced diet low in refined carbohydrates and sugars can help manage insulin levels.


Addressing Your Questions
1. Frequency of Inducing Menstruation: The frequency of taking medication to induce menstruation can vary. Some women may need it every few months, while others may require it more frequently. It is essential to work closely with your healthcare provider to determine the best schedule based on your individual needs.


2. Choosing Between Hormonal and Blood Sugar Medications: The choice between hormonal treatments and medications like Metformin depends on your specific symptoms and goals (e.g., managing menstrual cycles vs. improving insulin sensitivity). Both options have their benefits and potential side effects, which should be discussed with your healthcare provider.

3. Risk of Diabetes: Taking Metformin does not increase the risk of developing diabetes; in fact, it is often prescribed to prevent or manage insulin resistance, which is common in PCOS. However, maintaining a healthy lifestyle is crucial to minimize the risk of developing type 2 diabetes.

4. Diagnosis of PCOS: The diagnosis of PCOS can be made based on clinical symptoms, hormonal levels, and ultrasound findings. While some criteria suggest that symptoms should be present for a certain duration (like after menarche), your symptoms and lab results strongly indicate PCOS.

5. Diet and PCOS: Diet plays a significant role in managing PCOS. A diet rich in whole foods, including fruits, vegetables, lean proteins, and healthy fats, while minimizing processed foods and sugars, can help manage symptoms. Regular physical activity is also beneficial.


Conclusion
Managing PCOS is a multifaceted approach that includes medical treatment, lifestyle changes, and regular monitoring. It is essential to maintain open communication with your healthcare provider to tailor a treatment plan that addresses your specific symptoms and health goals. Regular follow-ups and adjustments to your treatment plan can help you manage PCOS effectively and improve your quality of life.

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