Cough: Tests and Concerns for Lung Health - Pulmonology

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Cough examination


Hello Doctor: I have been experiencing a persistent cough and some phlegm in my throat.
Besides getting a chest X-ray at the pulmonology department, what blood tests can I undergo to feel more at ease? How long does it typically take for lung cancer to develop from the initial stage to stage one? Is it necessary to have a lung CT scan every year? Is the radiation exposure from the scan significant?

Ms. Chen, 40~49 year old female. Ask Date: 2012/09/13

Dr. Yang Wenda reply Pulmonology


Hello Ms.
Chen: You have been experiencing respiratory symptoms for a long time! As a general principle, you should first consult a pulmonologist, who will conduct a thorough assessment based on their expertise.
The radiation exposure from a CT scan is significantly higher than that from a standard X-ray.
It is only recommended for high-risk groups (such as those with two or more family members with a history of lung cancer, individuals with a long history of smoking, or those who have been exposed to carcinogens like high air pollution, marble processing, steel mills, or asbestos industries) to undergo regular CT scans for early screening.
The development of lung cancer from the initial cellular mutation to stage one can take several years, but it typically needs to grow larger than 1 cm to be easily detected by a chest X-ray.
Best wishes!

Reply Date: 2012/09/13

More Info


Coughing can be a common symptom of various respiratory conditions, and understanding its underlying causes is crucial for effective management. Based on your concerns, it seems you are experiencing persistent cough with phlegm, which warrants further investigation to rule out serious conditions such as lung cancer or other pulmonary diseases.

When you visit a pulmonologist, they typically start with a physical examination and may recommend imaging tests like a chest X-ray or a CT scan. In addition to imaging, blood tests can provide valuable information about your overall health and help identify potential infections or inflammatory conditions. Common blood tests include:
1. Complete Blood Count (CBC): This test can help detect infections, anemia, and other blood disorders.

2. Eosinophil Count: Elevated eosinophils can indicate allergic reactions or parasitic infections.

3. Serum IgE Levels: This test measures the level of immunoglobulin E, which can be elevated in allergic conditions.

4. Tumor Markers: While not specific for lung cancer, certain markers can be elevated in malignancies and may warrant further investigation.

Regarding your question about lung cancer progression, the timeline for lung cancer development can vary significantly among individuals. Factors such as smoking history, exposure to carcinogens, and genetic predisposition play a role. Generally, lung cancer can take years to develop, and early-stage lung cancer may not present noticeable symptoms. The transition from a precancerous state to invasive cancer can take several years, but this varies widely.

As for the necessity of annual low-dose CT scans, this is often recommended for individuals at high risk for lung cancer, such as long-term smokers or those with a significant family history of lung cancer. The low-dose CT scan is designed to minimize radiation exposure while providing detailed images of the lungs. The radiation dose from a low-dose CT scan is significantly lower than that of a standard CT scan, and while there is some exposure to radiation, the benefits of early detection in high-risk populations often outweigh the risks.

If you are concerned about lung cancer or other serious conditions, it is essential to discuss your symptoms and risk factors with your healthcare provider. They can help determine the appropriate screening schedule based on your individual risk profile. In some cases, if initial tests are inconclusive or if there are concerning findings, further diagnostic procedures such as bronchoscopy or biopsy may be necessary to obtain a definitive diagnosis.

In summary, persistent cough with phlegm can be indicative of various conditions, and thorough evaluation through imaging and blood tests is essential for accurate diagnosis. Regular screenings may be necessary for high-risk individuals, and while radiation exposure is a consideration, the potential benefits of early detection of lung cancer are significant. Always consult with your healthcare provider to tailor a plan that best suits your health needs.

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