Can I Take Amoxicillin Before Tooth Extraction with Heart Conditions? - Pharmacology

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Hello, Doctor.
I have a benign fibroma in my chest and mitral valve prolapse with regurgitation.
I need to have a tooth extraction in a few days, and my cardiologist prescribed a total of eight Amoxicillin antibiotics, instructing me to take four capsules two hours before the procedure.
I forgot to mention my benign fibroma to the cardiologist.
I would like to ask: 1.
Is it safe for me to take this antibiotic? 2.
Due to my mitral valve prolapse, I sometimes experience difficulty breathing.
Are there any side effects from taking this medication that could affect me? Thank you, Doctor.

Tongxue, 20~29 year old female. Ask Date: 2012/11/30

Dr. Huang Yiping reply Pharmacology


Hello, prior to dental surgery, Amoxicillin is typically used for infection prophylaxis.
This medication generally has mild side effects, but caution is advised for patients with impaired kidney function.
Additionally, patients who have had allergic reactions to Amoxicillin or Penicillin should inform their physician, as it is usually recommended that individuals allergic to Penicillin avoid this medication.
If an allergic reaction occurs after taking the medication, such as difficulty breathing, skin redness, or itching, the medication should be discontinued immediately and medical attention sought.

Reply Date: 2012/11/30

More Info


When it comes to taking Amoxicillin before a tooth extraction, especially for patients with existing heart conditions such as mitral valve prolapse and benign fibromas, there are several important considerations to keep in mind.

1. Amoxicillin Usage: Amoxicillin is a commonly prescribed antibiotic that is often used to prevent infections, particularly in patients who are undergoing dental procedures. In your case, your cardiologist has prescribed Amoxicillin to be taken two hours before the extraction, which is a standard practice to reduce the risk of bacterial endocarditis—a serious infection that can occur when bacteria enter the bloodstream during dental work. Given that you have a benign fibroma in your chest, it is generally safe to take Amoxicillin, as this condition does not typically interfere with the antibiotic's efficacy or safety. However, it is crucial to inform your healthcare providers about all your medical conditions, including the benign fibroma, to ensure comprehensive care.

2. Potential Side Effects: While Amoxicillin is generally well-tolerated, it can cause side effects in some individuals. Common side effects include gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal pain. Allergic reactions, although rare, can occur and may present as rashes, itching, or more severe symptoms like difficulty breathing or swelling of the face and throat. Given your history of mitral valve prolapse, if you experience any respiratory issues after taking Amoxicillin, it is essential to seek medical attention immediately.
3. Impact on Heart Conditions: For patients with heart conditions, it is important to monitor how medications affect overall health. In your case, the concern about breathing difficulties related to mitral valve prolapse should be taken seriously. While Amoxicillin itself is not known to exacerbate heart conditions, any medication can have varying effects based on individual health profiles. If you notice increased shortness of breath or any other concerning symptoms after taking the antibiotic, you should contact your healthcare provider.

4. Communication with Healthcare Providers: It is vital to maintain open communication with your healthcare providers. Since you forgot to mention your benign fibroma to your cardiologist, consider discussing this with both your cardiologist and dentist before the extraction. They may want to reassess your treatment plan or provide additional precautions based on your complete medical history.

5. Pre-Extraction Considerations: Before undergoing tooth extraction, ensure you follow all pre-operative instructions provided by your dentist and cardiologist. This includes taking the prescribed antibiotics as directed, informing your dentist about your heart condition, and discussing any other medications you are currently taking, such as aspirin or warfarin, which may require adjustments to prevent excessive bleeding during the procedure.

In summary, taking Amoxicillin before your tooth extraction is generally safe, but it is essential to monitor for any side effects and communicate openly with your healthcare providers about your heart condition and any other medical issues. Always prioritize your health and safety by following the advice of your medical team.

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