Chronic Pelvic Pain: Is It Interstitial Cystitis? - Urology

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Regarding pain in the bladder area?


Hello Dr.
Hsu! I appreciate your help once again.
Thank you very much.
Around early September, I experienced symptoms of a urinary tract infection (burning sensation during urination, pain, and discomfort).
Western medicine tests showed 50-100 RBCs in my urine, but no bacteria, and WBCs were normal.
I was then treated as a typical urinary tract infection and prescribed antibiotics.
After 10 days, a follow-up urine test showed no hematuria, with 0-2 RBCs.

From September to December, I underwent two intravenous pyelograms, seven urine tests, one bacterial culture, kidney ultrasound, prostate ultrasound, PSA testing, digital rectal examination, and tests for gonorrhea, chlamydia PCR, syphilis, HIV, and herpes type 2, all of which were negative and normal.
The only tests not performed were urodynamics and cystoscopy.
Ultimately, my doctor concluded that I have chronic prostatitis due to burning sensations in my perineum and during bowel movements.
I was prescribed pain relief medication (Buscopan) and a urinary antiseptic.

Since then, I have been given the same medications (and of course, the physical therapies like warm sitz baths and hot compresses, which I’ve heard about more than ten times).
However, the burning sensation and pain in the urethra have hardly subsided.
Recently, in the last two weeks (from early to mid-December), I have been experiencing persistent bladder pressure and pain, accompanied by numbness, tingling, and burning sensations (with burning during urination).
The discomfort is more pronounced when my bladder is full or when sitting, but I also feel it when my bladder is not full (more comfortable after urination).
I usually wake up once at night to urinate, sometimes twice (once is more common).
During the day, I urinate quite frequently, estimating about 10 to 20 times a day (likely around 12 to 14 times).
I also experience urgency, feeling the need to urinate about 10 minutes after drinking water (though I can hold it).
The volume of urine is approximately 200 cc.
The pain is located about 5-7 cm below the navel, near the pubic area, and it radiates to both sides.
However, this burning sensation and discomfort almost completely disappear after lying down in bed for about 10 to 20 minutes (could it be that the bacteria also work from sunrise to sunset? Just a bitter smile...).
Taking a hot shower also provides some comfort.

I do not smoke or drink alcohol, and I maintain a light diet.
Since the suspected urethritis, I have been drinking about 1500-2000 cc of water daily.
Before the suspected urethritis, I exercised twice a week for about 30 minutes each time.
I have not engaged in any high-risk sexual behavior.

I would like to ask Dr.
Hsu: Could this be interstitial cystitis (IC)? Does the pain from IC subside when lying down? Is it possible that untreated urethritis has progressed to chronic cystitis? Are there any medical indications or mild forms of IC? I’m not saying I must think in terms of IC, but I see some symptoms that somewhat align with it.
I really don’t know what to do...
(Currently, I am seeking help from traditional Chinese medicine.) The Chinese medicine has had some effect; at least the pain is not as severe now...
Thank you for your response, Dr.
Hsu, and I wish you a Happy New Year.

david, 20~29 year old female. Ask Date: 2012/12/30

Dr. Xu Weikai reply Urology


David: Hello, IC (Interstitial Cystitis) usually occurs in women and is very rare in men.
Additionally, if traditional Chinese medicine is effective, it can be considered as a treatment option.
Physical therapies such as warm baths and localized massage can also be utilized.
Ultimately, you should engage in whatever makes you feel more comfortable; conversely, if something makes you feel worse, then you should avoid it.
If symptoms persist for too long, other causes, such as viral infections, should be considered.
These may not be detectable through standard cultures and may require special cultures.
Happy New Year!

Reply Date: 2012/12/30

More Info


Chronic pelvic pain (CPP) can be a complex and multifaceted condition, often leading to significant discomfort and distress for those affected. Your symptoms, including burning sensations in the urethra, pelvic discomfort, and urinary frequency, raise the possibility of interstitial cystitis (IC), also known as painful bladder syndrome. However, it's essential to consider various factors before arriving at a definitive diagnosis.

Firstly, interstitial cystitis is characterized by pelvic pain, pressure, or discomfort related to the bladder, often accompanied by urinary frequency and urgency. The pain associated with IC can vary in intensity and may improve when lying down, as you described. This improvement in pain when lying down could suggest that the pressure on the bladder is alleviated in this position, which is a common experience for individuals with IC. However, it is crucial to note that IC is a diagnosis of exclusion, meaning that other potential causes of your symptoms must be ruled out first.

Your medical history indicates that you have undergone extensive testing, including urine analysis, imaging studies, and various cultures, all of which returned normal results. The absence of bacteria in your urine, despite the presence of red blood cells, suggests that a typical urinary tract infection (UTI) may not be the cause of your symptoms. The diagnosis of chronic prostatitis, as suggested by your physician, could also explain some of your symptoms, particularly the burning sensation and discomfort in the pelvic region.

Chronic prostatitis can present with similar symptoms to IC, including pelvic pain, urinary urgency, and frequency. It is essential to consider that chronic pelvic pain syndromes can overlap, and one condition may coexist with another. In your case, the burning sensation in the urethra and pelvic area could be attributed to chronic prostatitis, while the bladder symptoms may suggest a component of IC.

Regarding your question about whether untreated urethritis could lead to chronic cystitis, it is possible. Chronic inflammation in the urinary tract can lead to changes in bladder function and sensitivity, potentially resulting in symptoms consistent with IC. However, this progression is not universally accepted and may vary from person to person.

As for the concept of "mild IC" or early signs of IC, there is ongoing research in this area. Some patients may experience symptoms that do not fully meet the criteria for IC but still cause significant discomfort. This condition is sometimes referred to as "bladder hypersensitivity" or "bladder pain syndrome," and it may respond to similar treatments as IC.

In terms of management, it is encouraging to hear that you have found some relief with traditional Chinese medicine (TCM). TCM can offer various approaches to managing chronic pain, including herbal remedies, acupuncture, and dietary modifications. These methods may help reduce inflammation and improve overall well-being.

It is also essential to continue working closely with your healthcare providers, including urologists and possibly pain specialists, to explore all potential treatment options. This may include medications specifically for IC, such as pentosan polysulfate sodium, bladder instillations, or other therapies aimed at managing chronic pelvic pain.

In conclusion, while your symptoms may align with interstitial cystitis, it is crucial to consider the broader context of your health and the possibility of overlapping conditions. Ongoing communication with your healthcare team and a comprehensive approach to treatment will be vital in managing your chronic pelvic pain effectively.

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