PSA Levels and Related Symptoms: A Urology Perspective - Urology

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Underwent testing?


Hello, Dr.
Hsu.
On January 26th at 8:30 AM, I had a blood test at the laboratory for PSA, and the result was 0.27 ng/ml, which is <4.
Given my age, is this normal? The night before the test, I only slept at 3:30 AM, and I usually stay up late.
I also had a light dinner of drunken chicken the night before the test.
I have a history of internal hemorrhoids and had a ligation surgery, but I still occasionally experience hard stools and anal fissures.
Could these factors affect the test results?
Additionally, my white blood cell count was 6300 on January 23rd, but it suddenly increased to 8800 on January 26th.
Is this abnormal? Could it indicate inflammation in some part of my body? For the past few days, I have experienced occasional dull or sharp pain near my left groin, with variable frequency.
The pain is not very deep and seems to be less noticeable when lying down, but more pronounced when sitting.
Last month, I had a testicular ultrasound, and the doctor did not mention any varicocele.
If it were a hernia, I don't see any bulging in my left groin, and there is no pain when I apply pressure.
What could these symptoms indicate?

aadda, 30~39 year old female. Ask Date: 2013/01/26

Dr. Xu Weikai reply Urology


AADDA: Hello.
1.
PSA: 0.27, which is normal.
2.
Elevated white blood cell count, still within normal range; further details should be examined, such as neutrophil levels.
3.
It is unclear whether inflammation is the cause.
Further testing is needed.
If there are any unclear points, feel free to ask again, and we can discuss and research further.
Responses from the internet should only be used as a reference; if necessary, it is important to seek medical care at a healthcare facility.
This message is from Dr.
Hsu Wei-Kai, Chief of Urology, Taitung Hospital, Department of Health, Executive Yuan, who cares about you.

Reply Date: 2013/01/26

More Info


Understanding PSA (Prostate-Specific Antigen) levels is crucial for assessing prostate health, particularly in men over the age of 50 or those with risk factors for prostate cancer. Your PSA level of 0.27 ng/ml is indeed below the commonly accepted threshold of 4.0 ng/ml, which is generally considered normal. However, PSA levels can be influenced by various factors, including age, prostate size, and other medical conditions.

In younger men, particularly those in their 30s and 40s, PSA levels are typically lower, and a level of 0.27 ng/ml is generally considered normal. It's important to note that PSA levels can fluctuate due to several reasons, including recent sexual activity, prostate manipulation (such as a digital rectal exam), or even certain medical procedures. In your case, the late-night eating of a rich meal like "burnt wine chicken" is unlikely to have a significant impact on your PSA levels, but lifestyle factors such as lack of sleep and stress can potentially affect overall health and hormone levels.

Regarding your white blood cell (WBC) count, a rise from 6,300 to 8,800 cells per microliter can indicate an inflammatory response or infection in the body. Normal WBC counts typically range from 4,000 to 11,000 cells per microliter, so your count is still within normal limits but on the higher side. This increase could be a response to a variety of factors, including stress, infection, or even recent physical activity. Given your symptoms of left groin discomfort, it would be prudent to monitor this closely, as localized pain could suggest a mild infection or inflammation.

The discomfort you are experiencing in the left groin area could be related to several conditions, including but not limited to, muscle strain, lymphadenopathy (swollen lymph nodes), or even issues related to the testicles or surrounding structures. Since you mentioned having had an ultrasound that did not reveal any varicocele, it may be worth considering other potential causes. Hernias, while often presenting with a visible bulge, can sometimes be present without obvious signs, especially in the case of an inguinal hernia.
If the pain persists or worsens, it would be advisable to consult with a urologist or general surgeon for a thorough evaluation. They may recommend further imaging studies or physical examinations to rule out any underlying conditions. Additionally, if you experience any other concerning symptoms, such as fever, significant changes in bowel habits, or urinary issues, you should seek medical attention promptly.

In summary, your PSA level appears normal for your age, and while the increase in WBC count is something to monitor, it is not necessarily alarming. The left groin pain warrants further investigation, especially if it continues or is accompanied by other symptoms. Regular follow-ups with your healthcare provider are essential for maintaining prostate health and addressing any emerging concerns.

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