Vaginal Suppository Side Effects: Itching and Discomfort - Obstetrics and Gynecology

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Using a suppository may cause itching?


Hello, Doctor: My sister gave me three doses of Clotrimazole suppositories.
I inserted one last night, and this morning I felt some itching and a burning sensation in my labia minora.
However, rinsing helps a bit.
I also noticed that my discharge is still yellow-green.
Doctor, am I experiencing an infection or inflammation? To be honest, I don't really like using suppositories because I'm worried they might cause my vaginal opening to become larger or looser.
Thank you.

huanzhe, 30~39 year old female. Ask Date: 2013/02/27

Dr. Lin Wenbin reply Obstetrics and Gynecology


Using suppositories will not cause the vaginal opening to become larger or looser.
If there are any uncomfortable reactions after using a suppository, it is advisable to consult the prescribing physician to determine whether it is safe to continue using them.

Reply Date: 2013/02/27

More Info


When using vaginal suppositories like Clotrimazole, it's not uncommon to experience side effects such as itching, burning sensations, or unusual discharge. These symptoms can be concerning, especially if you notice a yellow-green discharge, which may indicate an infection or inflammation.
Clotrimazole is an antifungal medication commonly used to treat yeast infections. While it is effective in eliminating fungal infections, it can also cause irritation in some individuals. The itching and burning you are experiencing could be a result of the medication itself, particularly if your body is sensitive to it or if there is an underlying irritation or infection that the suppository is exacerbating.

The yellow-green discharge you mentioned is particularly noteworthy. Normal vaginal discharge can vary in color and consistency, but a yellow-green hue often suggests the presence of an infection, such as bacterial vaginosis or a sexually transmitted infection (STI). It's essential to monitor this symptom closely. If the discharge persists, increases in volume, or is accompanied by a strong odor, it would be prudent to consult a healthcare provider for further evaluation.

Regarding your concern about the suppository causing vaginal laxity or enlargement, it's important to note that vaginal suppositories are designed to dissolve and be absorbed by the vaginal tissues. They do not typically cause any structural changes to the vagina. The vagina is a highly elastic organ, and while it can stretch, it generally returns to its normal state after the removal of any foreign object, including suppositories. If you have concerns about vaginal tone or laxity, discussing these with a healthcare provider can provide you with personalized advice and reassurance.

If you continue to experience discomfort or if you suspect an infection, it is advisable to stop using the suppository and seek medical advice. A healthcare provider can perform a thorough examination, possibly including a pelvic exam and laboratory tests, to determine the cause of your symptoms and recommend appropriate treatment. They may suggest alternative treatments or medications that are better suited to your needs and comfort level.

In summary, while some discomfort can be a normal reaction to vaginal suppositories, persistent symptoms, especially unusual discharge, warrant further investigation. Don't hesitate to reach out to a healthcare professional to ensure your health and well-being.

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