Parathyroid gland
Hello Doctor: My mother is 65 years old and recently had a health check-up.
The results showed that her parathyroid hormone level is 120, which is above the standard value.
She does not have any noticeable symptoms.
I would like to ask: 1.
Is this significantly above the standard value? 2.
Does she need treatment? What are the treatment options (medication or surgery)? 3.
What dietary considerations should she keep in mind? 4.
My mother has osteoporosis (though she feels she hasn't been tested), and she has been taking calcium supplements.
Will this affect the parathyroid hormone test? Is it safe for her to continue taking calcium? 5.
If the thyroid gland enlarges, what symptoms might the parathyroid gland cause? (My mother has difficulty turning her head to the right; could this be related to the parathyroid issue?) 6.
Is there a hereditary component to this condition? Thank you, Doctor.
Xiao Ru, 30~39 year old female. Ask Date: 2013/03/21
Dr. Cai Zonglin reply Internal Medicine
Each hospital may have slightly different standard values.
If parathyroid hormone levels are elevated, further evaluation of blood calcium levels or an ultrasound may be necessary.
In cases of parathyroid adenoma accompanied by hypercalcemia or osteoporosis, surgical intervention may be considered.
Certain osteoporosis medications can help manage osteoporosis symptoms, while calcium supplementation should take blood calcium levels into account; excessive supplementation is not recommended if hypercalcemia is already present.
Typically, parathyroid adenomas do not cause noticeable swelling in the neck.
To determine if a case involves a parathyroid disorder, further examination is required, and consultation with an endocrinologist is advisable.
Reply Date: 2013/03/21
More Info
Understanding parathyroid hormone (PTH) levels is crucial for assessing bone health and calcium metabolism in the body. Elevated PTH levels, such as your mother's reading of 120, can indicate several underlying health issues, particularly related to calcium levels and bone density.
1. Is the level significantly above the standard?
Normal PTH levels typically range from 10 to 65 pg/mL, depending on the laboratory and specific assay methods used. A level of 120 pg/mL is indeed elevated and suggests that the parathyroid glands are overactive, which could be due to primary hyperparathyroidism or secondary causes, such as vitamin D deficiency or chronic kidney disease.
2. Does she need treatment? How is it treated?
Treatment depends on the underlying cause of the elevated PTH. If primary hyperparathyroidism is diagnosed, surgical removal of the overactive parathyroid gland(s) may be necessary, especially if there are symptoms or complications such as kidney stones, osteoporosis, or significant hypercalcemia. If the elevation is secondary to another condition, addressing that condition (e.g., vitamin D supplementation) may suffice. It's essential to consult with an endocrinologist for a comprehensive evaluation and tailored treatment plan.
3. What dietary considerations should be made?
Diet plays a significant role in managing calcium and vitamin D levels. If your mother has elevated PTH, it may be beneficial to limit dietary calcium intake temporarily until the cause of the elevation is determined. However, if she has osteoporosis, adequate calcium and vitamin D intake is crucial for bone health. Foods rich in calcium include dairy products, leafy greens, and fortified foods. Vitamin D can be obtained from sunlight exposure and foods like fatty fish, egg yolks, and fortified products. A healthcare provider can recommend the best dietary approach based on her specific situation.
4. Will calcium supplements affect the parathyroid hormone levels?
Calcium supplements can influence PTH levels. If your mother is taking calcium supplements and has elevated PTH, it may be necessary to evaluate her calcium intake and adjust it accordingly. In some cases, excessive calcium supplementation can lead to further complications, especially if the underlying cause of elevated PTH is not addressed. It's advisable to discuss her calcium supplementation with her healthcare provider.
5. What symptoms are associated with parathyroid issues?
While the parathyroid glands themselves do not typically cause noticeable symptoms, elevated PTH can lead to symptoms related to hypercalcemia, such as fatigue, weakness, kidney stones, and bone pain. If there is a noticeable swelling in the neck, it could indicate thyroid issues rather than parathyroid problems. However, if your mother is experiencing difficulty turning her head, it may be worth investigating further, as this could be related to muscle or joint issues rather than directly linked to parathyroid function.
6. Is there a hereditary component?
Some forms of hyperparathyroidism can have a genetic component, particularly familial hyperparathyroidism syndromes. However, most cases of primary hyperparathyroidism occur sporadically. If there is a family history of parathyroid disorders or related conditions, it may be worth discussing this with her healthcare provider.
In summary, your mother's elevated PTH level warrants further investigation to determine the underlying cause and appropriate management. Regular follow-ups with her healthcare provider, including possible referrals to specialists, will be essential in managing her condition effectively.
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