Mediterranean Anemia: Concerns for Your Daughter's Health - Cardiology

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Blood test issues?


Hello Doctor: I have thalassemia and I'm concerned that my daughter may inherit it.
A year ago, my daughter's blood test results were as follows, and I would like to ask if she has anemia.
My daughter is 17 years old; can she take iron supplements or folic acid? Thank you!
Red Blood Cells (RBC) 4.68
Hemoglobin (HGB) 14.2
Hematocrit (Ht) 42.3
White Blood Cells (WBC) 7.24
Mean Corpuscular Volume (MCV) 90.3
Mean Corpuscular Hemoglobin (MCH) 30.4
Mean Corpuscular Hemoglobin Concentration (MCHC) 33.7
Platelets (PLT) 291
Additionally, I would like to ask if individuals with thalassemia should avoid iron supplements.
Can they take folic acid or B vitamins? Thank you for your response!

Miss Lin, 40~49 year old female. Ask Date: 2013/05/03

Dr. He Dongjin reply Cardiology


Hello, based on the report you provided, there are no signs of anemia, which is normal.
As for whether you can take iron supplements or folic acid, there are no contraindications; however, iron supplements are typically taken only if there is iron deficiency anemia, and folic acid is taken for macrocytic anemia.
Since there is no anemia present, additional supplementation may not be necessary.
Changhua Hospital cares about your health.

Reply Date: 2013/05/03

More Info


Mediterranean anemia, also known as thalassemia, is a genetic blood disorder characterized by reduced production of hemoglobin, which can lead to anemia. It is important to understand the implications of this condition, especially when considering the health of your daughter, who is 17 years old.

Based on the blood test results you provided for your daughter, her red blood cell (RBC) count is 4.68 million cells per microliter, hemoglobin (HGB) is 14.2 grams per deciliter, hematocrit (Ht) is 42.3%, white blood cell (WBC) count is 7.24 thousand cells per microliter, mean corpuscular volume (MCV) is 90.3 femtoliters, mean corpuscular hemoglobin (MCH) is 30.4 picograms, mean corpuscular hemoglobin concentration (MCHC) is 33.7 grams per deciliter, and platelet (PLT) count is 291 thousand cells per microliter. These values indicate that her hemoglobin levels are within the normal range for her age and gender, suggesting that she does not currently have anemia.

Regarding your concern about whether she can take iron supplements or folic acid, it is crucial to note that individuals with thalassemia should generally avoid iron supplementation unless they are diagnosed with iron deficiency anemia. This is because thalassemia patients often have normal or increased iron levels due to increased intestinal absorption of iron, and additional iron can lead to iron overload, which can damage organs such as the liver and heart.

As for folic acid and vitamin B complex, these can be beneficial. Folic acid is essential for the production of red blood cells and can help support overall blood health. It is often recommended for individuals with thalassemia to help manage their condition. Vitamin B12 is also important for red blood cell formation and can be taken if there is a deficiency.

In summary, your daughter does not appear to have anemia based on her blood test results. However, it is essential to monitor her health regularly, especially considering your family's history of Mediterranean anemia. If you have concerns about her iron levels or overall health, it would be prudent to consult with a hematologist or a healthcare provider specializing in blood disorders. They can provide personalized recommendations based on her specific health needs and family history.

Lastly, it is advisable to have genetic counseling to understand the risks of thalassemia inheritance and to discuss any preventive measures or treatments that may be appropriate for your daughter as she grows older. Regular check-ups and blood tests can help ensure that any potential issues are identified and managed early.

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