Managing Fever During Chemotherapy and Radiation Therapy - Oncology

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Chemotherapy and Radiation Therapy - Fever


Hello, doctor.
My family member is currently undergoing chemotherapy and radiation therapy, but yesterday they caught a cold and developed a fever of 38 degrees Celsius.
They went to a nearby clinic for an injection and medication, but today the fever has returned to 37.7 degrees Celsius.
What should we do in this situation? I am really worried because chemotherapy and radiation therapy can lower the immune system, and now with a cold, I am concerned about the impact on their treatment.
Thank you.

QQ, 30~39 year old female. Ask Date: 2013/05/13

Dr. Lai Yicheng reply Oncology


Hello, Sir: Combined chemotherapy and radiation therapy can cause side effects in the body.
On one hand, it requires the effort of the physician, and on the other hand, it requires the effort of the patient.
It is important to ensure adequate nutrition and sufficient sleep during this period.
Since chemotherapy can lead to a decrease in white blood cell count and a weakened immune system, it is advisable to minimize exposure to public places and practice self-protection measures, such as wearing a mask.
If you accidentally develop a fever or cold, the physician recommends resting for a few days to allow your body to recover before continuing treatment.
Whether this will affect your treatment may need to be discussed with your physician, as each individual's condition and response to treatment can vary.
Therefore, it is recommended that you consult with your physician during your outpatient visit.
~Changhua Hospital cares about you~

Reply Date: 2013/05/13

More Info


Managing fever during chemotherapy and radiation therapy can be a challenging aspect of cancer treatment, particularly because these therapies can significantly weaken the immune system. When a patient undergoing these treatments develops a fever, it is crucial to approach the situation with caution and care.

Firstly, it is essential to understand that fever can be a common side effect of chemotherapy and radiation therapy. These treatments can lead to neutropenia, a condition characterized by a low level of neutrophils (a type of white blood cell), which increases the risk of infections. In your family member's case, a fever of 38 degrees Celsius (100.4 degrees Fahrenheit) or higher should be taken seriously, especially since they are undergoing treatment that compromises their immune system.

Here are some steps to manage fever during chemotherapy and radiation therapy:
1. Monitor Temperature: Keep a close eye on the patient's temperature. If the fever persists or rises above 38.5 degrees Celsius (101.3 degrees Fahrenheit), it is essential to contact a healthcare provider immediately.

2. Hydration: Ensure that the patient stays well-hydrated. Fever can lead to dehydration, which can exacerbate the situation. Encourage the intake of fluids such as water, broth, or electrolyte solutions.

3. Rest: Encourage the patient to rest as much as possible. The body needs energy to fight off any potential infections.

4. Medications: Over-the-counter medications like acetaminophen (Tylenol) can be used to help reduce fever and alleviate discomfort. However, it is crucial to consult with a healthcare provider before administering any medication, especially in the context of ongoing cancer treatment.

5. Seek Medical Attention: Given that your family member is undergoing chemotherapy and radiation therapy, any fever should be reported to their oncologist or healthcare team. They may recommend blood tests to check for infections or other complications related to the treatment.

6. Preventive Measures: Since chemotherapy and radiation can lower immunity, it is vital to take preventive measures to avoid infections. This includes practicing good hygiene, avoiding crowded places, and wearing masks if necessary.

Regarding your concern about whether the fever will affect the treatment, it is essential to discuss this with the oncologist. In some cases, treatment may need to be delayed until the patient has recovered from the fever and any underlying infection. The oncologist will assess the situation based on the patient's overall health, the type of cancer, and the specific treatment plan.

In summary, while fever can be a common occurrence during chemotherapy and radiation therapy, it should not be ignored. Close monitoring, proper hydration, rest, and communication with healthcare providers are vital in managing this symptom effectively. Always prioritize safety and seek professional guidance when in doubt, as each patient's situation is unique and requires tailored care.

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