Managing Chronic Urticaria: Risks of Ignoring Symptoms and Treatment Options - Dermatology

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Chronic urticaria


Hello, doctor.
I developed chronic urticaria 21 years ago in high school (based on my personal research, it may be related to my frequent consumption of instant noodles during that time, and I have not been able to identify any allergens).
I saw a doctor a few years ago and took medication, but it only suppressed the symptoms without curing the condition, and the medication caused me to gain weight, so I stopped taking it.
I have now become accustomed to living with this condition.
I would like to ask the doctor: 1.
What are the potential negative effects of leaving chronic urticaria untreated? 2.
After 21 years, is there a possibility of achieving a cure with medication?

Dou Dou, 30~39 year old female. Ask Date: 2013/05/21

Dr. Li Yufen reply Dermatology


Hello: There are many causes of urticaria, including medications, foods, environmental allergens, and physical stimuli.
If it has progressed to chronic urticaria, sometimes medication only alleviates the symptoms and it can easily recur.
It is advisable to pay attention to where, when, or after what exposure the outbreaks occur, and see if you can draw any conclusions.
The potential drawbacks of chronic urticaria depend on the severity and frequency of your outbreaks.
If it does not affect your normal life, it is generally considered manageable.
Thank you!

Reply Date: 2013/05/21

More Info


Chronic urticaria, commonly known as chronic hives, is a condition characterized by recurrent episodes of itchy welts or hives on the skin that can last for six weeks or longer. Managing this condition effectively is crucial, as ignoring symptoms can lead to various complications and a significant impact on quality of life.


Risks of Ignoring Chronic Urticaria Symptoms
1. Quality of Life: Chronic urticaria can severely affect daily activities, sleep, and mental health. Persistent itching and discomfort can lead to anxiety, depression, and social withdrawal. Patients may find themselves avoiding social situations or activities they once enjoyed due to embarrassment or fear of an outbreak.

2. Skin Damage: Continuous scratching of hives can lead to skin damage, including infections, scarring, or changes in skin pigmentation. This can result in long-term dermatological issues that may require additional treatment.

3. Potential for Angioedema: In some cases, chronic urticaria can be associated with angioedema, which is swelling of the deeper layers of the skin. This can be particularly dangerous if it affects the throat or tongue, leading to difficulty breathing or swallowing.

4. Comorbid Conditions: Chronic urticaria can be associated with other health issues, such as autoimmune disorders. Ignoring symptoms may delay the diagnosis and treatment of these underlying conditions.


Treatment Options for Chronic Urticaria
1. Antihistamines: The first line of treatment for chronic urticaria typically involves non-sedating antihistamines. These medications can help control itching and reduce the frequency of hives. It's important to work with a healthcare provider to find the right dosage, as some patients may require higher doses than what is typically recommended.

2. Corticosteroids: For severe cases, short courses of corticosteroids may be prescribed to reduce inflammation and control symptoms. However, long-term use of corticosteroids is generally avoided due to potential side effects, including weight gain, osteoporosis, and increased risk of infections.

3. Omalizumab: This is a monoclonal antibody that has been shown to be effective in treating chronic urticaria that does not respond to antihistamines. It works by targeting IgE, a key player in allergic reactions, and can provide relief for patients who have not found success with traditional treatments.

4. Immunosuppressants: In some cases, medications that suppress the immune system may be considered, especially if there is an underlying autoimmune component to the urticaria.

5. Lifestyle Modifications: Identifying and avoiding triggers can be beneficial. Keeping a diary to track flare-ups and potential triggers (such as certain foods, stress, or environmental factors) can help in managing the condition.

6. Alternative Therapies: Some patients find relief through complementary therapies, such as acupuncture, dietary changes, or stress management techniques. However, these should be discussed with a healthcare provider to ensure they do not interfere with conventional treatments.


Can Chronic Urticaria Be Cured After 21 Years?
While chronic urticaria can be a long-lasting condition, many patients can achieve significant control of their symptoms with appropriate treatment. The possibility of "curing" chronic urticaria depends on several factors, including the underlying cause (if identifiable), the patient's overall health, and their response to treatment.
1. Reevaluation: It may be beneficial to reevaluate your condition with a healthcare provider who specializes in allergies or dermatology. They can perform a thorough assessment, including potential allergy testing or investigations for underlying conditions.

2. Long-term Management: While complete resolution may not be possible for everyone, many patients find that with the right combination of treatments, they can manage their symptoms effectively and improve their quality of life.

In conclusion, ignoring chronic urticaria can lead to various complications, and it is essential to seek appropriate treatment. While a complete cure may not be guaranteed, many treatment options are available that can help manage symptoms and improve overall well-being. Regular follow-ups with a healthcare provider can ensure that the treatment plan is effective and adjusted as needed.

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