Can I Use Aifumei and Kelistin During Early Pregnancy? - Dermatology

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Hello, I have a history of allergies and had atopic dermatitis as a child, but it has mostly resolved in adulthood.
Recently, around five and a half weeks into my pregnancy, I have developed allergic reactions on both cheeks, appearing inflamed, red, swollen, and dry.
This occurred once last winter as well, and I have been using Aifumei for treatment.
However, since I am in the early stages of pregnancy, I am unsure if this medication is safe to use.
If it is safe, what would be the appropriate dosage to use as a guideline? (For example, a pea-sized amount?)
Additionally, I have another question.
I visited a dermatologist today, and the doctor prescribed Clindamycin gel.
I found out that this is an antibiotic, and the package insert clearly states it has teratogenic effects, which makes me quite skeptical about the prescribing doctor! Therefore, I would like to ask again, is this medication safe? Thank you!

Ms. Hsieh, 30~39 year old female. Ask Date: 2013/06/04

Dr. Lin Xinpeng reply Dermatology


Hello: Elomet (mometasone furoate) is classified as a Category C medication by the FDA for use in pregnant women.
This classification means that animal studies have shown adverse effects on the embryo (such as teratogenicity or embryotoxicity), but there are no adequate and well-controlled studies in pregnant women; or there are no controlled studies in pregnant women or animals.
This medication should only be used when the potential benefits outweigh the risks.
Although mometasone is classified as Category C, its structure and potency make it suitable for use on the cheeks or for children, so you can use it with confidence.
However, it is generally not recommended to use topical corticosteroids continuously for more than two weeks during pregnancy.
The application should be a thin layer sufficient to cover the affected area.
Based on your clinical symptoms, in addition to applying the corticosteroid ointment, it is advisable to enhance moisturization or apply lotion, which may shorten the treatment duration and reduce the time of corticosteroid use.
As for Clindamycin, it is an antibiotic classified as Category B by the FDA, which means that animal studies have not demonstrated a risk to the fetus; however, there is insufficient evidence from human studies.
Theoretically, it is recommended for use in dermatological topical applications.
If you still have concerns, you may consider using another antibiotic, such as erythromycin, which is also a Category B topical antibiotic.

Reply Date: 2013/06/04

More Info


During early pregnancy, the use of medications requires careful consideration due to potential risks to the developing fetus. In your case, you are asking about the safety of using Aifumei (which is likely a topical medication for skin conditions) and Kelistin (an antibiotic).
Firstly, let's address Aifumei. This medication is often used to treat skin conditions, including allergic reactions and dermatitis. While topical medications generally have a lower risk of systemic absorption compared to oral medications, it is still important to consider the specific ingredients and their safety profiles during pregnancy. If Aifumei contains corticosteroids or other potent active ingredients, it may be classified as a Category C drug, which means that risk cannot be ruled out. It is advisable to use the smallest effective amount and apply it only to the affected areas. A common guideline is to use a pea-sized amount for a localized area, but this can vary based on the specific product and the area being treated. Always consult your healthcare provider for personalized advice.

Now, regarding Kelistin, which is an antibiotic, it is crucial to be cautious. Antibiotics can have varying effects during pregnancy, and some are contraindicated due to potential teratogenic effects (causing malformations in the fetus). If the prescribing physician has indicated that Kelistin is necessary for your condition, it is essential to discuss the risks and benefits with them. The presence of a warning about teratogenic effects on the medication's label should not be taken lightly. If you have concerns about the safety of this antibiotic, you may want to seek a second opinion from another healthcare provider.

In general, the use of any medication during pregnancy should be approached with caution. The following considerations are essential:
1. Necessity of Treatment: Ensure that the medication is necessary for your health condition. If the allergic reaction is manageable without medication, it may be worth considering non-pharmacological approaches, such as avoiding triggers or using moisturizers.

2. Safety Profile: Always check the safety category of the medication. Category A drugs are considered safe, while Category C drugs should be used only if the benefits outweigh the risks.
3. Consultation with Healthcare Providers: Always discuss any medications with your healthcare provider, especially during pregnancy. They can provide guidance based on the latest research and your specific health needs.

4. Monitoring for Side Effects: If you decide to use these medications, monitor for any adverse effects on yourself or any signs that could indicate a problem with the pregnancy. Report any unusual symptoms to your healthcare provider immediately.

In conclusion, while some topical medications may be safe during early pregnancy, it is crucial to evaluate each medication's risks and benefits. Always consult with your healthcare provider before starting or continuing any medication during pregnancy to ensure the safety of both you and your developing baby.

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