Exploring Ginkgo Biloba for Vertebral Artery Syndrome: Risks and Interactions - Neurology

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The use of ginkgo preparations?


My father has been experiencing long-term dizziness.
After undergoing a vascular ultrasound, he was diagnosed with Vertebral Artery Syndrome.
However, due to the length of the blockage, surgery is not recommended, and he is only on medication for maintenance.
His dizziness symptoms have not worsened.
I would like him to try ginkgo biloba supplements, but the doctor does not recommend it.
Is there a high risk involved? Currently, he is taking the following medications: Acetylsalicylic Acid, Dihydroergotoxine, Amlodipine, Dipyridamole, Estazolam, and Betahistine Mesylate.
Are there any interactions?

Zong Yilong, 40~49 year old female. Ask Date: 2013/07/12

Dr. Liu Yanliang reply Neurology


Currently, there is insufficient evidence to support the effectiveness of ginkgo biloba in the prevention of stroke.
Additionally, the medications your father is taking, Acetylsalicylic Acid and Dipyridamole, are already classified as cardiovascular drugs.
It appears that your attending physician has provided recommendations that are consistent with medical standards; please confirm this with your physician.

Reply Date: 2013/07/12

More Info


Ginkgo biloba, a popular herbal supplement, is often explored for its potential benefits in improving blood circulation and cognitive function. However, when considering its use for conditions like Vertebral Artery Syndrome (VAS), particularly in patients already on multiple medications, it is crucial to understand the associated risks and potential interactions.

Vertebral Artery Syndrome is characterized by symptoms such as dizziness, vertigo, and sometimes even neurological deficits due to compromised blood flow in the vertebral arteries. This condition can arise from various factors, including atherosclerosis, cervical spine issues, or other vascular problems. In your father's case, the diagnosis indicates a significant blockage that is not amenable to surgical intervention, necessitating a careful approach to management.

The medications your father is currently taking include:
1. Acetyl Salicylic Acid (Aspirin): This is an antiplatelet medication that helps prevent blood clots.

2. Dihydroergotoxine: Often used to improve cerebral blood flow and alleviate symptoms of vascular insufficiency.

3. Amlodipine: A calcium channel blocker that helps manage hypertension and can improve blood flow.

4. Dipyridamole: Another antiplatelet agent that can enhance blood flow and is sometimes used in combination with aspirin.

5. Estazolam: A benzodiazepine used for anxiety and sleep disorders, which may have sedative effects.

6. Betahistine Mesylate: Commonly used to treat vertigo and balance disorders, particularly in Meniere's disease.

Given this medication regimen, introducing Ginkgo biloba could pose several risks. Ginkgo biloba is known to have blood-thinning properties, which may enhance the effects of antiplatelet medications like aspirin and dipyridamole. This could potentially increase the risk of bleeding, especially in patients with vascular issues. Additionally, Ginkgo can interact with other medications, leading to unpredictable effects on blood pressure and circulation.

Furthermore, Ginkgo biloba may cause side effects such as gastrointestinal upset, headaches, dizziness, and allergic skin reactions. In some cases, it can also lead to more severe complications, such as bleeding disorders, particularly in individuals with existing vascular conditions or those on anticoagulant therapy.

Given your father's current health status and medication regimen, it is advisable to consult with a healthcare provider, preferably a neurologist or a specialist in vascular medicine, before introducing Ginkgo biloba or any new supplement. They can provide a comprehensive evaluation of his condition, assess the potential benefits versus risks of Ginkgo biloba, and monitor for any adverse interactions with his existing medications.

In conclusion, while Ginkgo biloba may have potential benefits for improving circulation, its use in patients with Vertebral Artery Syndrome, particularly those on multiple medications, should be approached with caution. The risks of bleeding and interactions with current medications must be carefully weighed against any potential benefits. Always prioritize open communication with healthcare providers to ensure safe and effective management of your father's condition.

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