Is Surgery Necessary for 12cm Asymptomatic Focal Nodular Hyperplasia? - Gastroenterology and Hepatology

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Focal Nodular Hyperplasia (FNH) of the liver


Hello Doctor: I would like to ask if a 12 cm asymptomatic focal nodular hyperplasia (FNH) of the liver requires surgery, or if it can be monitored instead? Thank you!

JoJo, 30~39 year old female. Ask Date: 2013/07/11

Dr. Chen Shidian reply Gastroenterology and Hepatology


Please discuss in person with your physician to clarify any potential risks (including bleeding) and whether monitoring is sufficient.

Reply Date: 2013/07/11

More Info


Focal Nodular Hyperplasia (FNH) of the liver is a benign condition characterized by the presence of a well-circumscribed mass of liver tissue that contains a central scar and is composed of normal liver cells. It is important to note that FNH is generally asymptomatic and does not progress to malignancy. Given your situation of having a 12 cm asymptomatic FNH, the decision regarding surgery versus observation can be nuanced and should be made in consultation with your healthcare provider.

In most cases, surgery is not necessary for asymptomatic FNH, especially if the diagnosis is confirmed through imaging studies such as ultrasound, CT, or MRI. These imaging modalities typically show characteristic features of FNH, which can help differentiate it from other liver lesions, such as hepatic adenomas or hepatocellular carcinoma. The key point is that FNH is not associated with any significant risk of complications or progression to cancer, which is a primary concern when considering surgical intervention.

The management of FNH often involves a watchful waiting approach, particularly for larger lesions that are asymptomatic. Regular follow-up with imaging studies every 6 to 12 months is usually recommended to monitor the lesion for any changes in size or characteristics. If the lesion remains stable and asymptomatic, there is generally no need for surgical intervention. However, if there are any changes in the lesion or if symptoms develop, further evaluation may be warranted.

In your case, since the FNH is 12 cm and asymptomatic, it is advisable to discuss the potential risks and benefits of surgery versus continued observation with your healthcare provider. Factors to consider include the size of the lesion, any potential symptoms that may arise, and your overall health status. If you have any underlying liver disease or other comorbidities, these factors may influence the decision-making process.

In summary, surgery is not typically necessary for a 12 cm asymptomatic FNH. Instead, a strategy of regular monitoring and follow-up imaging is often the preferred approach. It is crucial to maintain open communication with your healthcare provider to ensure that any changes in your condition are promptly addressed. If you have any concerns or experience new symptoms, do not hesitate to reach out for further evaluation.

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