Morning Urination Issues: Causes and Treatment Options - Urology

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Difficulty urinating in the morning?


Dear Dr.
Lin,
My younger brother previously had a tumor in the urogenital area, which has been treated and he has recovered.
However, his bladder capacity remains small (150-250 cc during the day) and is somewhat better at night (300-400 cc).
Recently, after visiting a urologist, he was prescribed "Oxybutynin Extended-Release Tablets," to be taken once daily.
After about a week of use, there has been no significant improvement in bladder capacity.
In the past three days, he has experienced a problem where he has a very small urine output upon waking up in the morning, needing to urinate 2-3 times to completely empty his bladder.
This difficulty in urination is only present in the morning right after waking up; urination after getting out of bed is normal.
Could this be a side effect of the medication, or could there be other possible causes? Thank you.

Youzi, 30~39 year old female. Ask Date: 2013/08/23

Dr. Lin Hexing reply Urology


Hello: Actually, your bladder capacity is quite good.
This type of medication relaxes the bladder detrusor muscle, which may relatively affect urinary function and lead to difficulties in urination.
If there are no significant symptoms of frequency or urgency, there is no need to take the medication.
Wishing you good health.

Reply Date: 2013/08/23

More Info


Morning urination issues can be quite distressing, especially when they interfere with daily life. In your brother's case, it seems that he has a history of urinary and reproductive issues due to a tumor, which can complicate bladder function. The medication he is currently taking, "Oxybutynin" (often referred to as "欧舒缓释锭" in Chinese), is an anticholinergic agent commonly used to treat overactive bladder symptoms. While it can be effective in managing bladder control, it also comes with potential side effects that may contribute to the symptoms your brother is experiencing.


Understanding the Causes
1. Bladder Capacity: Your brother's reported bladder capacity of 150-250cc during the day and 300-400cc at night indicates a reduced bladder capacity, which can lead to frequent urination. A normal bladder can hold about 400-600cc of urine. The reduced capacity might be a result of his previous medical condition or the treatment he underwent.

2. Medication Side Effects: Oxybutynin can cause side effects such as dry mouth, constipation, dizziness, and urinary retention. In some cases, it may also lead to difficulty in urination, especially if the bladder is not able to contract effectively. The fact that your brother is experiencing difficulty urinating in the morning could be related to the medication, particularly if he is taking it at night or if it is affecting his bladder's ability to contract properly upon waking.

3. Post-Micturition Dribbling: The need to urinate multiple times in the morning with a weak stream may also suggest that he is experiencing post-micturition dribbling, which can occur when the bladder does not empty completely. This can be exacerbated by medications that affect bladder function.

4. Other Factors: Other potential causes for morning urination difficulties could include dehydration, urinary tract infections, or even anxiety, which can affect bladder function. Given his medical history, it is also essential to consider any psychological factors that may contribute to his symptoms.


Treatment Options
1. Medication Review: It is crucial for your brother to discuss his symptoms with his urologist. The doctor may consider adjusting the dosage of Oxybutynin or switching to another medication that may have fewer side effects. There are alternative medications available for overactive bladder, such as tolterodine or solifenacin, which might be better tolerated.

2. Bladder Training: Implementing a bladder training program could help improve bladder capacity and control. This involves scheduled urination times and gradually increasing the intervals between urination.

3. Pelvic Floor Exercises: Strengthening the pelvic floor muscles through exercises like Kegel exercises can improve bladder control and reduce symptoms of urgency and frequency.

4. Hydration Management: Monitoring fluid intake, especially before bedtime, can help manage nighttime urination. However, it is essential to ensure he stays adequately hydrated throughout the day.

5. Follow-Up: Regular follow-ups with the urologist are essential to monitor bladder function and adjust treatment as necessary. If symptoms persist or worsen, further diagnostic tests may be required to rule out any underlying issues.

In conclusion, while the medication your brother is taking may be contributing to his morning urination difficulties, it is essential to consider all potential factors, including his medical history and current treatment plan. Open communication with his healthcare provider will be key in finding an effective solution to manage his symptoms and improve his quality of life.

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