Axillary Lymph Node Enlargement: When to Seek Further Evaluation - Oncology

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Axillary lymphadenopathy


Hello Doctor: I have a history of asthma.
Recently, I had a persistent cough, so I visited a pulmonologist.
After blood tests and an X-ray, the doctor diagnosed me with a Mycoplasma infection causing bronchitis, and prescribed antibiotics and cough medication.
I took the antibiotics for about three weeks.
However, the week before last, I suddenly felt a lump in my armpit.
It was not very painful when pressed and could move around.
I went back to the pulmonologist, who said it was an enlarged lymph node measuring about 1.5 cm (only through palpation, no further tests were conducted) and that it would resolve on its own.
No additional medication was prescribed.
Should I see an oncologist for further evaluation? Additionally, how long might this enlargement last? I have not experienced any trauma; why would I have an enlarged lymph node in my armpit? I am a bit worried about the lump in my armpit, so I would appreciate your clarification.
Thank you!

wirklich, 30~39 year old female. Ask Date: 2013/08/28

Dr. Chen Sirong reply Oncology


Hello! Inflammation and cancer can both cause lymphadenopathy.
Lymph nodes affected by cancer tend to continue enlarging and becoming harder, while inflamed lymph nodes are generally softer and often resolve on their own, although a small percentage may persist.
However, it can be challenging for patients to distinguish between the two, which can be concerning.
1.
Should I go back to the oncology department for further examination? I recommend that you continue to follow up with your original pulmonologist weekly, as they will be more familiar with any changes in size and hardness of the lymph nodes.
A new doctor may not have the context of your lymph nodes' previous characteristics.
2.
How long might this enlargement last? It could last around a month, but some individuals may have persistent residual enlargement.
3.
I have no history of trauma; why is there swelling in my axillary lymph nodes? Tumors do not require an open wound to cause inflammation.
There are numerous pathways through which bacteria or viruses can enter the body, making it impossible to list them all.
Finally, I suggest you continue to monitor the situation, and if the lymph nodes continue to enlarge or harden, seek medical attention.
Thank you for your inquiry.
Taoyuan Hospital, Chen Si-Rong

Reply Date: 2013/08/28

More Info


When it comes to axillary lymph node enlargement, it is essential to understand the underlying causes and when further evaluation is warranted. In your case, you have a history of asthma and recently experienced a respiratory infection, which was diagnosed as a Mycoplasma infection leading to bronchitis. After a course of antibiotics, you noticed a lump in your axilla (armpit) that was approximately 1.5 cm in size.
Lymph nodes can become enlarged for various reasons, including infections, inflammation, and malignancies. In your situation, the enlargement of the axillary lymph node could be a reactive process due to the recent infection. Lymph nodes often swell in response to infections as they play a crucial role in the immune response, filtering pathogens and producing immune cells. The fact that the lymph node is movable and not painful is generally a good sign, as painful and fixed lymph nodes can sometimes indicate a more serious condition.

Your doctor has assessed the lymph node through physical examination and has indicated that it may resolve on its own without the need for further intervention or medication. This is a common scenario, especially when the lymph node enlargement is associated with a recent infection. However, it is crucial to monitor the situation closely.

Here are some guidelines on when to seek further evaluation for axillary lymph node enlargement:
1. Duration: If the lymph node remains enlarged for more than 2-4 weeks after the resolution of the infection, it may warrant further investigation. Persistent lymphadenopathy can sometimes indicate an underlying condition that needs to be addressed.

2. Size: A lymph node larger than 1 cm in diameter, especially if it continues to grow, should be evaluated further. In your case, since it is 1.5 cm, it is on the borderline, but given your recent infection, it may still be reactive.

3. Characteristics: If the lymph node becomes hard, fixed to surrounding tissues, or if you experience systemic symptoms such as unexplained weight loss, night sweats, or fever, these could be red flags that necessitate further evaluation.

4. Associated Symptoms: If you develop new symptoms, such as persistent cough, difficulty breathing, or any other concerning signs, it would be prudent to seek further medical advice.

5. Imaging Studies: If the lymph node does not decrease in size or if there are concerns based on physical examination, your doctor may recommend imaging studies such as an ultrasound or CT scan to further evaluate the lymph node.

In your case, since your doctor has advised that the lymph node may resolve on its own, it may not be necessary to see an oncologist immediately. However, if you have ongoing concerns or if the lymph node does not decrease in size over the next few weeks, it would be wise to follow up with your healthcare provider. They may refer you to a specialist if needed.

As for the duration of lymph node enlargement, it can vary significantly depending on the underlying cause. In cases of infection, lymph nodes may remain enlarged for several weeks to months even after the infection has resolved.
In summary, while your current situation may not require immediate further evaluation, it is essential to remain vigilant. Monitor the lymph node for changes in size or characteristics, and do not hesitate to reach out to your healthcare provider if you have any concerns or if new symptoms arise. Your health and peace of mind are paramount, and proactive communication with your healthcare team is key to managing your condition effectively.

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