Recently, there was hematuria?
Hello doctor, I recently had hematuria and underwent a urinalysis.
The results showed urine protein at 600, red blood cells at 100, and white blood cells at 20-35.
The doctor said it was a bladder infection.
However, can inflammation cause an increase in urine protein? Thank you.
A-Kun, 20~29 year old female. Ask Date: 2013/10/19
Dr. Lin Hexing reply Urology
Hello: Inflammation can lead to changes in proteinuria.
Generally, if there is no history of proteinuria, it should resolve after the inflammation is treated.
Otherwise, one should suspect that there may be an underlying kidney disease.
In such cases, it is necessary to follow up with a nephrologist for further examination.
Lastly, I want to emphasize that a repeat urine test should be conducted after the treatment of inflammation to ensure that the treatment has been fully effective.
Wishing you good health.
Reply Date: 2013/10/19
More Info
Yes, bladder inflammation, also known as cystitis, can indeed lead to elevated protein levels in the urine. When the bladder is inflamed, it can cause damage to the bladder lining, which may allow proteins, such as albumin, to leak into the urine. This condition is referred to as proteinuria, and it can be detected through urinalysis.
In your case, the urinalysis results show a significant amount of protein (600 mg/dL) and a notable presence of red blood cells (100) and white blood cells (20-35). The presence of red blood cells in the urine, known as hematuria, along with proteinuria, can indicate that there is some form of injury or irritation occurring in the urinary tract. Inflammation of the bladder can be caused by various factors, including infections, irritants (such as certain medications or chemicals), or even underlying conditions like interstitial cystitis.
When the bladder is inflamed, the increased permeability of the bladder wall can lead to the leakage of proteins into the urine. This is particularly true in cases of acute cystitis, where the inflammation is often due to a bacterial infection. The white blood cells present in your urine may also suggest an inflammatory response, which is common in urinary tract infections (UTIs).
It is important to note that while bladder inflammation can cause proteinuria, it is not the only possible cause. Other conditions, such as kidney disease, glomerulonephritis, or nephrotic syndrome, can also lead to elevated protein levels in the urine. Therefore, it is essential to consider the entire clinical picture, including symptoms, medical history, and additional tests, to determine the underlying cause of your proteinuria and hematuria.
If your doctor has diagnosed you with bladder inflammation, they may recommend treatment options such as antibiotics if an infection is present, or anti-inflammatory medications to help reduce the inflammation. It is also advisable to follow up with your healthcare provider for further evaluation and monitoring of your kidney function and urinary symptoms.
In summary, bladder inflammation can indeed raise protein levels in the urine due to damage to the bladder lining, leading to protein leakage. Given your urinalysis results, it is crucial to work closely with your healthcare provider to address the underlying cause of your symptoms and to monitor your urinary health. Regular follow-up tests may be necessary to assess the resolution of inflammation and to ensure that there are no other underlying conditions affecting your urinary system.
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