Is Colonoscopy Safe During Pregnancy After Positive Stool Test? - Gastroenterology and Hepatology

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Is it appropriate to undergo a colonoscopy during pregnancy if fecal occult blood (not from hemorrhoids) is detected?


Hello, doctor.
I had a health check-up shortly after becoming pregnant (in mid-August this year) and found that my stool occult blood test was positive.
In November, I consulted a gastroenterologist for an internal examination, and there were no signs of internal or external hemorrhoids.
In a situation where I felt helpless, I took another stool occult blood test, which still came back positive.
After researching online, it seems that the next step in testing would be a colonoscopy, but it appears that undergoing a colonoscopy during pregnancy may not be advisable.
I am also concerned that if I wait until after giving birth next year to get checked, any potential disease could worsen.
I would like to ask if there are any other suitable tests for pregnant women? Or, since I am already four months pregnant, is it safe to undergo a colonoscopy? Thank you!

Pang Niu, 30~39 year old female. Ask Date: 2013/11/13

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Hello: If routine stool tests show a positive result, it may indicate bleeding from the mouth to the anus.
If an Enzyme Immunoassay (EIA) is used, it is more focused on detecting lower gastrointestinal bleeding.
A digital rectal exam cannot completely rule out internal hemorrhoids.
Performing an upper gastrointestinal endoscopy during pregnancy is generally acceptable, but a colonoscopy requires more consideration; it is usually safe within the first four months of pregnancy, but not advisable later on.
If there is no absolute necessity, it is better to wait until after delivery.
Wishing you safety and health.
Sincerely, Dr.
Chi-Feng Chen, Gastroenterology Department, Taoyuan General Hospital, Ministry of Health and Welfare.

Reply Date: 2013/11/13

More Info


Colonoscopy during pregnancy is a complex issue that requires careful consideration of both the potential risks and benefits. Given your situation, where you have had a positive stool test for occult blood and are concerned about the possibility of underlying gastrointestinal issues, it is understandable that you are seeking clarity on the next steps.

First, it is important to acknowledge that a positive stool occult blood test can indicate a variety of conditions, ranging from benign issues such as hemorrhoids or fissures to more serious conditions like polyps or colorectal cancer. The fact that you have already undergone an examination by a gastroenterologist and found no external abnormalities is reassuring, but it does not completely rule out the need for further investigation.

When it comes to performing a colonoscopy during pregnancy, the general consensus in the medical community is that it is usually safe, particularly in the second trimester (weeks 14-27). The first trimester is often avoided due to the higher risk of miscarriage, and the third trimester can pose challenges due to the size of the uterus and the potential for complications during the procedure. However, if there is a strong clinical indication for the procedure, such as significant gastrointestinal symptoms or a high suspicion of a serious condition, it may still be performed with appropriate precautions.

In your case, since you are already four months pregnant, you are in the second trimester, which is typically considered the safest time for a colonoscopy. The procedure can be performed with minimal sedation, which is generally safe for the fetus. However, it is crucial to discuss this with your healthcare provider, who can evaluate your specific situation, consider your medical history, and assess the urgency of the colonoscopy based on your symptoms and the results of your stool tests.

If a colonoscopy is deemed necessary, your healthcare provider will take steps to minimize any risks. This may include using a lower level of sedation, monitoring you closely during the procedure, and ensuring that the procedure is performed in a facility equipped to handle any potential complications.

As for alternative tests, if a colonoscopy is not immediately pursued, there are other non-invasive options that may be considered. For instance, imaging studies such as an abdominal ultrasound or MRI can provide information about the gastrointestinal tract without the need for invasive procedures. However, these tests may not provide the same level of detail as a colonoscopy.

In summary, while a colonoscopy during pregnancy is generally safe, it is essential to weigh the risks and benefits with your healthcare provider. Given your positive stool test and the absence of other findings, it may be prudent to proceed with the colonoscopy, especially since you are in the second trimester. Always ensure that you have a thorough discussion with your healthcare provider about your concerns, the necessity of the procedure, and any alternative options that may be available. Your health and the health of your baby are of utmost importance, and your healthcare team will work with you to ensure the best possible outcome.

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