Hepatitis B: Testing Negative After Possible Exposure - Gastroenterology and Hepatology

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Hepatitis B


Last month, while having dinner with a friend, I accidentally drank from a beverage he had consumed.
This friend has hepatitis B.
The next day, which was last Tuesday, I went to the hospital for a blood test.
Yesterday, I reviewed the report, and it showed that the hepatitis B surface antigen was negative, while the hepatitis B surface antibody was reactive.
Does this confirm that I was not infected with hepatitis B during the gathering with my friend last Monday?

Di Ke, 30~39 year old female. Ask Date: 2014/02/17

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Hello: It is definitely not the case.
Hepatitis B is not transmitted through food, and there is an incubation period.
You likely have antibodies and have developed immunity.
Wishing you peace and good health.
Sincerely, Dr.
Chi-Feng Chen, Gastroenterology, Taoyuan General Hospital, Ministry of Health and Welfare.

Reply Date: 2014/02/17

More Info


Based on the information you provided regarding your recent Hepatitis B test results, it appears that you have a clear understanding of your current health status concerning Hepatitis B. Your test results indicate that the Hepatitis B surface antigen (HBsAg) is negative, while the Hepatitis B surface antibody (anti-HBs) is reactive. Let's break down what these results mean in the context of your potential exposure to Hepatitis B from your friend.

1. Understanding HBsAg and anti-HBs:
- HBsAg (Hepatitis B Surface Antigen): This is a protein on the surface of the Hepatitis B virus. The presence of HBsAg in your blood indicates an active Hepatitis B infection. Since your result is negative, it suggests that you are not currently infected with the virus.

- anti-HBs (Hepatitis B Surface Antibody): This antibody is produced by your immune system in response to the Hepatitis B virus or after vaccination. A reactive anti-HBs result indicates that you have immunity against Hepatitis B, either from a past infection that your body has cleared or from vaccination.

2. Implications of Your Results:
- Given that your HBsAg is negative and your anti-HBs is reactive, it is highly likely that you have not contracted Hepatitis B from your friend during your recent encounter. The negative HBsAg confirms that there is no active infection, while the reactive anti-HBs suggests that you have developed immunity, which protects you from future infections.

- If you had been exposed to the virus and subsequently infected, you would expect to see a positive HBsAg result. Since that is not the case, your risk of having contracted the virus from your friend is very low.

3. Further Considerations:
- It is important to note that Hepatitis B is primarily transmitted through blood and bodily fluids. While sharing drinks can pose a risk, the likelihood of transmission through saliva is significantly lower compared to direct blood exposure. Therefore, your situation appears to be low risk.

- If you have any concerns about your immunity status or if you have not been vaccinated against Hepatitis B, you might consider discussing with your healthcare provider the possibility of vaccination. Vaccination is a safe and effective way to ensure long-term protection against Hepatitis B.

4. Follow-Up:
- Since you have confirmed immunity with your reactive anti-HBs, there is generally no need for further testing unless you develop symptoms or have other risk factors. However, regular check-ups and discussions with your healthcare provider are advisable to maintain your overall health.

In conclusion, based on your test results, you can be reassured that you have not contracted Hepatitis B from your recent exposure. Your body has developed immunity, which is a positive outcome. If you have any further questions or concerns, do not hesitate to reach out to your healthcare provider for personalized advice and guidance.

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