Mycoplasma Pneumonia in Children: Symptoms and Treatment Options - Pediatrics

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About Mycoplasma pneumoniae!


Hello Dr.
Hsiao: My younger sister has been coughing for over a month.
Last week, she had a blood test, and the results were as follows:
- White blood cell count: 13.5 (units: 1000/uL, normal range: 6.7–11.8)
- Red blood cell count: 4.89 (units: million/uL, normal range: 4.28–5.05)
- Hemoglobin: 13.7 (units: g/dL, normal range: 11.6–13.7)
- Hematocrit: 40.3 (units: %, normal range: 34.2–39.8)
- Mean corpuscular volume: 82.4 (units: fL, normal range: 74.9–84.6)
- Mean corpuscular hemoglobin: 28 (units: pg/cell, normal range: 25.2–29.1)
- Mean corpuscular hemoglobin concentration: 34 (units: gHb/dL, normal range: 32.6–35.1)
- Red cell distribution width: 38.5 (units: fL, normal range: 38–47.5)
- Platelet count: 390 (units: 1000/uL, normal range: 150–400)
- Red cell distribution width coefficient of variation: 12.8 (units: %, normal range: 11–14.7)
- Neutrophils: 61.7 (units: %, normal range: 13.9–49.5)
- Lymphocytes: 33 (units: %, normal range: 44.7–81.6)
- Monocytes: 4.7 (units: %, normal range: 1.3–7.2)
- Eosinophils: 0.4 (units: %, normal range: 0.0–4.3)
- Basophils: 0.2 (units: %, normal range: 0–1)
She has been diagnosed with a Mycoplasma pneumonia infection, with a titer of 826.5 U/mL (standard value: Negative <770).
She is currently being treated with Azithromycin for two days, but she is still coughing (with phlegm).
My sister is currently two years and one month old.
Would performing a sputum test be helpful for her recovery?
Additionally, besides the Mycoplasma pneumonia infection, she has also been tested for allergies to milk and egg proteins, with an allergy index of 2.
Is this considered severe? Should she completely avoid milk and egg proteins? Based on the above indices, are there any other conditions that my sister might have besides the Mycoplasma pneumonia infection?

Zhuang Tai Tai, 30~39 year old female. Ask Date: 2014/03/14

Dr. Xiao Kaiwen reply Pediatrics


A normal two-year and one-month-old child should have sufficient strength to cough up phlegm (although sometimes they may swallow it).
Chest physiotherapy is not necessary.
The blood test report you provided is just a basic blood examination, with the only notable abnormality being an elevated white blood cell count, which can be caused by many factors such as infection, stress, or steroid use, and it does not allow us to determine if there are any other underlying conditions.
There are several methods for specific allergen immunological testing, and the interpretation values vary, so I cannot comment on your value of "2."

Reply Date: 2014/03/14

More Info


Mycoplasma pneumoniae infection is a common cause of pneumonia in children, particularly in those aged 5 to 15 years. It is often referred to as "walking pneumonia" because the symptoms can be mild and may not require hospitalization. Understanding the symptoms, treatment options, and management strategies for this condition is crucial for parents and caregivers.


Symptoms of Mycoplasma Pneumonia
The symptoms of Mycoplasma pneumonia can vary but typically include:
1. Persistent Cough: Often dry at first, it may become productive (with phlegm) as the infection progresses.

2. Fever: Low-grade fever is common, but it can sometimes be higher.

3. Sore Throat: Many children report a sore throat, which can accompany the cough.

4. Fatigue: Children may feel unusually tired or lethargic.

5. Chest Pain: Some children may complain of chest discomfort, especially when coughing.

6. Shortness of Breath: This can occur, particularly in more severe cases.

In your sister's case, the persistent cough for over a month, along with the positive test for Mycoplasma pneumoniae, aligns with typical symptoms of this infection.


Treatment Options
The primary treatment for Mycoplasma pneumonia involves the use of antibiotics, as this bacterium is resistant to penicillin. Commonly prescribed antibiotics include:
- Macrolides (e.g., Azithromycin or Clarithromycin): These are often the first line of treatment for children.

- Tetracyclines (e.g., Doxycycline): These are generally used for older children and adolescents.

- Fluoroquinolones: These are reserved for more severe cases or when other antibiotics are not effective.

In your sister's case, she is currently being treated with a medication called "日舒" (likely referring to Azithromycin or a similar macrolide), which is appropriate for Mycoplasma pneumonia. It is important to complete the full course of antibiotics as prescribed, even if symptoms improve.


Management of Symptoms
In addition to antibiotics, supportive care is essential. This includes:
- Hydration: Ensuring she stays well-hydrated can help thin mucus and ease coughing.

- Rest: Adequate rest is crucial for recovery.

- Cough Management: If the cough is productive, encouraging her to cough can help clear mucus. However, if it is dry and bothersome, a cough suppressant may be considered, but this should be discussed with her healthcare provider.

Regarding your question about "拍痰" (postural drainage or chest physiotherapy), this can sometimes help in clearing mucus from the lungs, especially if she has a productive cough. However, it is essential to consult with her healthcare provider before starting any new treatments or therapies.


Allergies to Milk and Egg
You mentioned that your sister has allergies to milk and egg proteins. An allergy index of 2 indicates a mild sensitivity, but it is essential to monitor her reactions closely. If she has had adverse reactions to these foods, it is advisable to avoid them entirely until further evaluation by an allergist can be conducted. Allergies can manifest in various ways, including skin reactions, gastrointestinal symptoms, or respiratory issues.


Additional Considerations
Based on the lab results you provided, her white blood cell count is slightly elevated, which can indicate an ongoing infection or inflammation. The presence of Mycoplasma pneumoniae infection is significant, but it is also essential to monitor her overall health and any other symptoms that may arise.

If her cough persists despite treatment, or if she develops new symptoms such as high fever, difficulty breathing, or chest pain, it is crucial to follow up with her pediatrician for further evaluation. They may consider additional diagnostic tests or imaging studies to assess her lung health and rule out any complications.

In summary, Mycoplasma pneumoniae is a treatable infection, and with appropriate antibiotic therapy and supportive care, most children recover well. Monitoring her allergies and maintaining communication with her healthcare provider will ensure she receives the best care possible.

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