Blood Test Results: Is My Child at Risk for Thalassemia? - Cardiology

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Complete Blood Count (CBC)


Hello, Doctor.
My son underwent a hematocrit test, and the results are as follows: WBC: 6.67, RBC: 5.23, HB: 16.2, HCT: 44.4, MCV: 84.9, MCH: 31.0, MCHC: 36.5, Platelet: 197, RDW-SD: 35.2.
The last value, the red blood cell distribution width standard deviation, is highlighted in red, with a normal range of 39-52.3.
Could you please tell me if this indicates thalassemia? Should I have my child consume iron-rich foods?

meg, 50~59 year old female. Ask Date: 2014/04/21

Dr. He Dongjin reply Cardiology


Hello, don't be too nervous.
That number doesn't have much significance; the main thing to look at is the Hb, which is very high.
There is no issue with anemia, so please rest assured.
Changhua Hospital cares about you.

Reply Date: 2014/04/21

More Info


When interpreting blood test results, especially in the context of potential conditions like thalassemia, it is crucial to consider the complete blood count (CBC) and the specific parameters that indicate red blood cell (RBC) characteristics. Your child's results show the following key values:
- WBC (White Blood Cells): 6.67 (normal range)
- RBC (Red Blood Cells): 5.23 (normal range)
- Hemoglobin (HB): 16.2 (normal range)
- Hematocrit (HCT): 44.4 (normal range)
- MCV (Mean Corpuscular Volume): 84.9 (normal range)
- MCH (Mean Corpuscular Hemoglobin): 31.0 (normal range)
- MCHC (Mean Corpuscular Hemoglobin Concentration): 36.5 (normal range)
- Platelet Count: 197 (normal range)
- RDW-SD (Red Cell Distribution Width): 35.2 (slightly low compared to the normal range of 39-52.3)

Understanding the Results
1. Red Blood Cell Indices: The MCV, MCH, and MCHC values are all within normal ranges, which indicates that the average size and hemoglobin content of the red blood cells are typical. In thalassemia, you would often see microcytic (smaller than normal) and hypochromic (less color due to lower hemoglobin) red blood cells, which does not appear to be the case here.

2. RDW-SD: The RDW-SD value is slightly low. RDW measures the variation in the size of red blood cells. A normal RDW indicates that the red blood cells are of similar size, while a high RDW can suggest a mix of different sizes, which is often seen in various types of anemia, including thalassemia. However, a low RDW does not typically indicate thalassemia.

3. Hemoglobin Levels: Your child's hemoglobin level is within the normal range for children, which is a positive sign. Thalassemia often presents with lower hemoglobin levels.


Risk for Thalassemia
Based on the provided results, there is no strong indication that your child has thalassemia. The normal values for hemoglobin, MCV, MCH, and MCHC suggest that the red blood cells are functioning properly. Thalassemia is characterized by specific abnormalities in these parameters, particularly low hemoglobin levels and microcytic red blood cells.


Dietary Considerations
While your child’s blood test results do not indicate thalassemia, it is always beneficial to maintain a balanced diet rich in iron and other nutrients that support blood health. Foods such as leafy greens, beans, lentils, red meat, and fortified cereals can help ensure adequate iron intake. However, since your child’s hemoglobin levels are normal, there may not be an immediate need for iron supplementation unless advised by a healthcare provider.


Recommendations
1. Follow-Up: It is advisable to discuss these results with your pediatrician or a hematologist for a comprehensive evaluation. They may recommend further testing if there are any clinical concerns or family history of thalassemia or other blood disorders.

2. Monitor Symptoms: Keep an eye on any symptoms that may arise, such as fatigue, pallor, or unusual bruising, and report these to your healthcare provider.

3. Healthy Diet: Encourage a balanced diet that supports overall health, which can help in maintaining optimal blood parameters.

In conclusion, while the blood test results do not suggest thalassemia, it is essential to maintain regular check-ups and consult with healthcare professionals for personalized advice and monitoring.

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