Benign Tumors: Risks, Recurrence, and Monitoring - Oncology

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Benign tumor


Hello Doctor, during elementary school, I discovered a tumor growing on the lower right mandible.
At that time, a biopsy was performed to determine whether the tumor was malignant or benign, and the result was a benign pleomorphic adenoma.
The doctor also informed me that due to my constitution, it was highly likely that it would recur.
Sure enough, it has grown back, and now there are tumors on both sides, not just one, and their sizes fluctuate.
Although it does not affect my daily life, I am concerned about the possibility of it transforming into a malignant tumor.
Should I continue to have regular follow-ups?

Judy, 20~29 year old female. Ask Date: 2014/06/13

Dr. Chen Sirong reply Oncology


Judy needs to continue monitoring the following: 1.
Self-awareness 2.
She must see a doctor if any of the following conditions occur: 2.1 Increase in size 2.2 Change in color 2.3 Hardening 2.4 Uncomfortable symptoms, such as pain caused by nerve compression 2.5 Infection, including redness, swelling, heat, and pain.
Thank you for your letter, Dr.
Chen Sih-Rong, Taoyuan Hospital.

Reply Date: 2014/06/13

More Info


Understanding benign tumors, particularly in the context of your experience with a pleomorphic adenoma (commonly known as a benign tumor of the salivary glands), involves several key aspects: the nature of benign tumors, their potential for recurrence, monitoring strategies, and the risks associated with them.


Nature of Benign Tumors
Benign tumors, such as pleomorphic adenomas, are generally non-cancerous growths that do not invade surrounding tissues or metastasize to other parts of the body. They are often well-circumscribed and can be removed surgically with a low risk of recurrence if excised completely. However, some benign tumors, particularly those in the salivary glands, can recur if not entirely removed or if they have a tendency to grow back due to their cellular characteristics.


Recurrence and Monitoring
As you mentioned, your doctor indicated that due to your body’s predisposition, there is a significant chance that the tumor could recur. This is not uncommon with pleomorphic adenomas, which can sometimes reappear after surgical removal. The recurrence rate can vary, but studies suggest that it can be as high as 10-20% if the tumor is not completely excised.

Given that you have experienced recurrence on both sides of your jaw, it is essential to monitor these growths. While benign tumors are not cancerous, they can cause discomfort, functional issues, or cosmetic concerns, depending on their size and location. Regular follow-ups with your healthcare provider are advisable to assess the growths for any changes in size, shape, or symptoms.


Risk of Malignant Transformation
One of the concerns with benign tumors, particularly pleomorphic adenomas, is the potential for malignant transformation. Although this is relatively rare, it can occur, especially if the tumor has been present for a long time or if there have been multiple recurrences. The risk of transformation into a malignant form, such as carcinoma ex pleomorphic adenoma, is estimated to be around 1-5%. Therefore, it is crucial to remain vigilant and report any new symptoms, such as pain, rapid growth, or changes in the texture of the tumor.


Recommendations for Follow-Up
1. Regular Monitoring: It is advisable to have regular check-ups with your healthcare provider, who may recommend imaging studies (like ultrasound or MRI) to monitor the size and characteristics of the tumors. This is particularly important if you notice any changes.

2. Surgical Consideration: If the tumors become bothersome or if there is a significant change in their characteristics, surgical intervention may be necessary. Discussing the possibility of a more extensive surgical approach with your surgeon could be beneficial, especially if there is a concern about recurrence.

3. Symptom Management: If the tumors are asymptomatic and not affecting your quality of life, a conservative approach with regular monitoring may be appropriate. However, if you experience discomfort or functional issues, it may be worth considering surgical options.

4. Lifestyle Considerations: Maintaining a healthy lifestyle, including a balanced diet and regular exercise, can support your overall health and may help in managing benign tumors.


Conclusion
In summary, while benign tumors like pleomorphic adenomas are not cancerous, they require careful monitoring due to the potential for recurrence and, in rare cases, malignant transformation. Regular follow-ups with your healthcare provider are essential for managing your condition effectively. If you have any concerns or notice changes in your tumors, do not hesitate to reach out to your doctor for further evaluation and guidance.

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