Medication Effects on Mental Health: A Patient's Journey

Medication issues

Hello, Doctor.
I am currently taking two capsules of Wellbutrin daily, but during my recent health check, my first GPT result came back elevated.
Could this be related to the medication? In the past, when I took medications like Youjiet (Venlafaxine) or Luvox (Fluvoxamine), I could feel their effects quite clearly.
However, now that I’m taking two capsules daily, I don’t feel particularly happy and don’t experience emotional fluctuations.
I feel like I’m often worried and anxious, but the doctor says it’s depression.
I’ve been on the medication for over a month, and I’m confused about whether I need to firmly believe that it will help me for the medication to be effective, or if there’s something I can do to feel better every day.

nana, 30~39 year old female. Ask Date: 2014/06/16

Dr. Lin Junyuan reply Psychiatry

Hello, as far as I know, the term "Wan You Jie" you mentioned does not refer to a specific pharmacological name, so it is difficult to determine which medication you are referring to.
Generally speaking, antidepressants are considered safe as long as they are taken according to a physician's instructions and potential drug interactions are avoided.
Regarding elevated GPT levels, there could be many possible causes, and it may be advisable to follow up with a gastroenterologist for further related tests.
During your consultation, in addition to discussing symptoms, you should also address lifestyle, work, and personal habits that may be environmental triggers related to anxiety or depression.
I recommend following your physician's current advice.
If medication treatment and environmental adjustments are appropriately managed, most patients show significant improvement within two months.
Best wishes to you!

Reply Date: 2014/06/16

More Info

Understanding the effects of medication on mental health can be a complex journey, particularly for individuals dealing with conditions like depression and anxiety. Your experience with medications such as Lexapro (escitalopram) and others highlights the challenges many face in managing their mental health effectively.
Firstly, it’s important to recognize that medications like SSRIs (Selective Serotonin Reuptake Inhibitors), which include Lexapro, are designed to help regulate serotonin levels in the brain. This neurotransmitter plays a crucial role in mood regulation, and imbalances can lead to symptoms of depression and anxiety. However, the effectiveness of these medications can vary significantly from person to person. Some individuals may experience noticeable improvements in mood and anxiety levels, while others may not feel a significant change, even after adjusting dosages or trying different medications.

In your case, it seems that despite taking a higher dosage of medication, you are not experiencing the emotional uplift you might expect. This can be frustrating and may lead to feelings of confusion or hopelessness. It’s crucial to communicate these feelings with your psychiatrist, as they can help assess whether the current medication is appropriate or if adjustments are needed. Sometimes, it may take several trials of different medications or combinations to find what works best for you.

Regarding your concern about the recent lab results indicating elevated GPT levels, it’s essential to discuss this with your healthcare provider. Some medications can affect liver function, and your doctor may want to monitor this closely or consider alternative treatments if necessary. It’s vital to ensure that your physical health is not compromised while managing your mental health.

You mentioned feeling a lack of emotional highs and lows, which can be a common experience for individuals on antidepressants. Some people describe this as feeling emotionally "flat." While medications can help stabilize mood, they can also dampen emotional responses. This is why therapy, particularly cognitive-behavioral therapy (CBT), can be beneficial alongside medication. Therapy can provide you with tools to manage anxiety and depression more effectively, helping you to process emotions and develop coping strategies.

In terms of feeling anxious and troubled, it’s important to engage in self-care practices that can enhance your overall well-being. Regular physical activity, a balanced diet, adequate sleep, and mindfulness practices such as meditation or yoga can significantly impact your mental health. Additionally, maintaining a support network of friends and family can provide emotional support and help alleviate feelings of isolation.

Lastly, it’s essential to have realistic expectations about medication. While it can be a powerful tool in managing mental health, it is not a cure-all. It’s often most effective when combined with lifestyle changes and therapeutic interventions. If you feel uncertain about your treatment plan, don’t hesitate to seek a second opinion or consult with a mental health professional who can provide additional insights.

In summary, your journey with medication and mental health is unique, and it’s essential to work closely with your healthcare provider to find the right balance. Open communication about your experiences, side effects, and concerns will empower you to take an active role in your treatment. Remember, it’s okay to seek help and explore various avenues for improving your mental health.

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