Hepatitis B: Negative Antibodies and Vaccination Recommendations - Gastroenterology and Hepatology

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Hepatitis B


The presence of negative antibody-antigen results does not necessarily indicate that you have hepatitis B.
The report suggests that you should consider getting vaccinated.

Mǎyǐ, 20~29 year old female. Ask Date: 2014/07/07

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Hello: If the surface antigen and antibodies are negative, and anti-HBc is present, it indicates that the individual has never been infected and has not been vaccinated.
Vaccination should be administered.
Wishing you peace and health.
Dr.
Chi-Feng Chen, Gastroenterology Department, Taoyuan General Hospital, Ministry of Health and Welfare.

Reply Date: 2014/07/07

More Info


When it comes to understanding Hepatitis B, the presence or absence of antibodies and antigens in your blood test results is crucial in determining your infection status and the need for vaccination. Based on the information you've provided, your test results show that both the Hepatitis B surface antigen (HBsAg) and the Hepatitis B surface antibody (anti-HBs) are negative. This means that you do not currently have an active Hepatitis B infection and you also do not have immunity against the virus.

To clarify, the Hepatitis B surface antigen (HBsAg) is a protein on the surface of the Hepatitis B virus. If this antigen is present in your blood, it indicates that you are currently infected with the virus, either acutely or chronically. Conversely, the Hepatitis B surface antibody (anti-HBs) indicates that you have either recovered from a past infection or have been vaccinated against Hepatitis B and developed immunity. Since both of your results are negative, it suggests that you have neither an active infection nor immunity to Hepatitis B.

The recommendation for vaccination in your case is appropriate. Vaccination against Hepatitis B is highly effective and is the best way to prevent infection. The vaccine is typically administered in a series of three doses, which can provide long-lasting immunity. Given that you have no current immunity and are not infected, receiving the vaccine will help protect you from potential future exposure to the virus.

It's also important to understand the implications of being unvaccinated. Hepatitis B is transmitted through contact with infectious body fluids, such as blood, semen, and vaginal secretions. This can occur through various means, including unprotected sexual contact, sharing needles, or from mother to child during childbirth. Therefore, being vaccinated significantly reduces your risk of contracting the virus.

In summary, your negative test results indicate that you do not have Hepatitis B and lack immunity. The recommendation to get vaccinated is a proactive measure to protect your health. It's advisable to follow through with the vaccination schedule and consult with your healthcare provider for any further questions or concerns regarding Hepatitis B and your overall health. Vaccination not only protects you but also contributes to the broader public health goal of reducing the incidence of Hepatitis B infections in the community.

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