Can Twins Receive Oral Rotavirus Vaccine at 6 Months Old? - Pediatrics

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Oral rotavirus vaccine


Hello, Dr.
Hsiao.
I would like to ask if it is still possible to administer the oral rotavirus vaccine to my twin children who are nearly 6 months old.
I previously read online that administering the first dose after 3 months could increase the risk of intussusception, but the doctor said it was fine.
I'm unsure what to do.
If it is possible to proceed, does their current age mean we can only choose the 3-dose vaccine? Thank you!

Penny, 30~39 year old female. Ask Date: 2014/08/13

Dr. Xiao Kaiwen reply Pediatrics


The Rotarix vaccine is approved for use up to 24 weeks of age (approximately six months) at the time of its launch, as its clinical trials only included infants under 24 weeks.
The RotaTeq vaccine, which is a three-dose series, can be used up to 32 weeks of age.
However, the United States has since raised the upper age limit for both rotavirus vaccines (Rotarix and RotaTeq) to eight months.
Therefore, while it is likely safe to administer Rotarix to infants over 24 weeks, the official regulation in Taiwan still remains at 24 weeks.
It is advisable to discuss with your doctor which vaccine to use.
Based on my personal experience, administering the two-dose Rotarix vaccine to infants aged 6 to 7 months did not present any significant issues.

Reply Date: 2014/08/13

More Info


When considering the administration of the oral rotavirus vaccine for your twins who are nearly six months old, it is important to understand the guidelines and recommendations surrounding this vaccine. The rotavirus vaccine is crucial for preventing severe gastroenteritis caused by rotavirus, which can lead to dehydration and hospitalization in infants and young children.

There are two main types of rotavirus vaccines available: Rotarix (which is a two-dose vaccine) and RotaTeq (which is a three-dose vaccine). According to the guidelines, the Rotarix vaccine is typically administered at 2 and 4 months of age, while RotaTeq is given at 2, 4, and 6 months. The maximum age for the first dose of Rotarix is 24 weeks (approximately 6 months), and for RotaTeq, it is 32 weeks. However, in the United States, the age limit for both vaccines has been extended to 8 months, although local regulations may vary.

Since your twins are approaching 6 months, they are still within the acceptable age range for receiving the rotavirus vaccine, provided they have not yet received any doses. If they have not yet been vaccinated, it is advisable to discuss with your pediatrician whether to administer the vaccine now or to wait until they are older.
Regarding the concern about intussusception (a condition where part of the intestine folds into another section, which can occur after rotavirus vaccination), it is true that there is a slight increased risk of this condition following the first dose of the vaccine, particularly in infants aged 3 to 12 months. However, the overall risk is very low, and the benefits of vaccination in preventing severe rotavirus disease generally outweigh this risk. Your pediatrician's reassurance that it is safe to proceed with the vaccination is consistent with current medical guidelines.

If you decide to proceed with vaccination, it is essential to note that if your twins are to receive the RotaTeq vaccine, they will need to complete all three doses to ensure adequate protection. If they are receiving Rotarix, they will only need the two doses. Given their age, if they have not received any doses yet, they can still receive either vaccine, but it is crucial to follow the recommended schedule.

In summary, your twins can receive the oral rotavirus vaccine at this age, and it is advisable to consult with your pediatrician to determine the best course of action based on their vaccination history and health status. Vaccination is a key preventive measure against rotavirus, and ensuring that your children are vaccinated will help protect them from severe gastrointestinal illness. Always remember that maintaining good hygiene practices, such as regular handwashing, is also essential in preventing the spread of infections, including rotavirus.

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