Managing Stomach Ulcers: Transitioning from PPI to Antacids - Gastroenterology and Hepatology

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About three years ago, I started taking a proton pump inhibitor (PPI)?


Is it normal to switch to antacids after four months due to a gastric ulcer? Do I need to undergo another endoscopy? I've been taking antacids for about two and a half to almost three years.
The oral taste associated with excessive stomach acid and gastric ulcers should disappear, right? How should I manage my situation? When the gastric ulcer heals, will all abnormal symptoms associated with the ulcer disappear?

Wo de chenghu, 40~49 year old female. Ask Date: 2014/08/22

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello: Long-term use of either PPIs or antacids is not recommended.
If there are no ulcer symptoms, it is not necessary to undergo follow-up endoscopy after treatment.
If ulcer symptoms are present, a physician should evaluate whether follow-up endoscopy is necessary.
If there is excessive gastric acid, symptoms should be corrected through lifestyle changes or dietary adjustments, rather than relying on medication long-term.
The term "gastric scarring" likely refers to the fibrotic changes in the mucosa after the healing of an ulcer.
Changhua Hospital cares about your health.

Reply Date: 2014/08/22

More Info


Transitioning from Proton Pump Inhibitors (PPIs) to antacids for managing stomach ulcers is a common practice, but it is essential to understand the implications of such a change and the ongoing management of your condition.
First, it is important to recognize that PPIs and antacids serve different purposes in the treatment of gastric conditions. PPIs, such as omeprazole or lansoprazole, work by significantly reducing the production of stomach acid, which helps heal ulcers and manage conditions like gastroesophageal reflux disease (GERD). On the other hand, antacids, such as aluminum hydroxide or magnesium hydroxide, neutralize existing stomach acid and provide quick relief from symptoms but do not promote healing of the ulcer itself.

If you have been on PPIs for four months and are now considering a switch to antacids, this could be a normal step in your treatment plan, especially if your symptoms have improved. However, it is crucial to consult with your healthcare provider before making this transition. They can assess your current condition and determine whether this change is appropriate based on your symptoms and any underlying issues.

Regarding the need for repeat endoscopy (gastroscopy), it depends on several factors, including the severity of your symptoms, the duration of your ulcer, and your overall health. If you have been symptom-free for an extended period and your healthcare provider believes that the ulcer has healed, they may not recommend another endoscopy. However, if you continue to experience symptoms or if there are concerns about the healing process, an endoscopy may be warranted to evaluate the state of your stomach lining and ensure that there are no complications, such as bleeding or malignancy.

As for the oral taste associated with excessive stomach acid, this symptom should ideally diminish as your ulcer heals and your acid levels normalize. However, if you continue to experience an unpleasant taste or other symptoms, it may indicate that further evaluation is necessary.
When it comes to managing your condition, it is essential to maintain a diet that supports gastric health. Avoiding spicy, acidic, or irritating foods can help minimize symptoms. Additionally, lifestyle modifications such as eating smaller, more frequent meals, avoiding late-night eating, and managing stress can also contribute to better outcomes.

In summary, transitioning from PPIs to antacids can be a normal part of managing stomach ulcers, but it is essential to do so under the guidance of your healthcare provider. Regular follow-up appointments and possibly repeat endoscopies may be necessary to monitor your condition and ensure that your ulcer is healing properly. If you have concerns about persistent symptoms or the effectiveness of your current treatment plan, do not hesitate to reach out to your healthcare provider for further evaluation and guidance.

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