Semen Analysis: Beyond Liquefaction Time Issues - Urology

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In addition to prolonged liquefaction time, are there any other issues?


Hello, Dr.
Hsu.
I just received the lab report, and aside from the liquefaction time being significantly outside the normal range, are there any other indices that show abnormalities? What lifestyle changes or medical treatments should I consider? Additionally, does liquefaction time have a significant impact on fertility? Previous Q&As mentioned that factors like constitution, infection, and inflammation could contribute to this issue.
How should I address these concerns or seek medical assistance?
Appearance: Gray-White
Consistency: Mucoid
pH: 7.5
Volume: 2 mL
Liquefaction time: 120 min
Sperm Count: 81,500,000 /mL
Morphology normal: 81%
Morphology abnormal: 19%
RBC: 2-3 /HPF
WBC: 2-3 /HPF
Epithelial cells: 2-3 /HPF
Rapid progressive motility: 20%
Slow progressive motility: 32%
Non-motile: 48%

OOO, 30~39 year old female. Ask Date: 2014/08/23

Dr. Xu Weikai reply Urology


Hello, your motility is relatively poor, specifically the progressive motility, which is generally expected to be greater than 50%.
Additionally, the percentage of non-motile sperm should ideally be below 40%.
Furthermore, the volume of ejaculation is quite low, typically around 5 milliliters.
The liquefaction time is prolonged, but this will not affect fertility.
This is usually due to a deficiency in a specific enzyme or reduced enzyme activity.
If there are any unclear points, feel free to ask again, and we can discuss and research further.
Online responses can only serve as a reference; if necessary, it is important to seek medical attention at a healthcare facility.
This message is from Dr.
Hsu Wei-Kai, Chief of Urology, Taitung Hospital, Ministry of Health and Welfare.

Reply Date: 2014/08/23

More Info


Understanding semen analysis is crucial for assessing male fertility, and it involves evaluating various parameters, including liquefaction time, sperm count, motility, and morphology. Based on the report you provided, there are several key points to consider regarding your semen analysis results and their implications for fertility.


Key Findings from Your Semen Analysis
1. Liquefaction Time: Your liquefaction time is reported at 120 minutes, which is significantly longer than the normal range (typically 15 to 30 minutes). Prolonged liquefaction can hinder sperm motility and, consequently, fertility. It may indicate issues such as infection or inflammation in the reproductive tract.

2. Sperm Count: Your sperm count is 81.5 million/mL, which is within the normal range (typically above 15 million/mL). This is a positive aspect of your analysis.

3. Sperm Motility: The motility results show that 20% of sperm are rapidly progressive, 32% are slow progressive, and 48% are non-motile. While the total motility (52%) is within the acceptable range (above 40%), the proportion of rapidly progressive sperm is relatively low. This could affect the sperm's ability to reach and fertilize an egg.

4. Sperm Morphology: With 81% of sperm showing normal morphology, this is a good sign, as a higher percentage of normal forms is associated with better fertility potential.

5. Presence of RBCs and WBCs: The presence of 2-3 red blood cells (RBCs) and 2-3 white blood cells (WBCs) per high power field (HPF) may indicate some underlying issues, such as inflammation or infection, which could also contribute to prolonged liquefaction time.


Implications for Fertility
The prolonged liquefaction time can indeed impact fertility. Sperm need to liquefy properly to swim effectively and reach the egg. If the liquefaction is delayed, it can lead to decreased motility and, ultimately, lower chances of conception.

Recommendations for Improvement
1. Lifestyle Modifications:
- Diet: Incorporate a balanced diet rich in antioxidants (fruits, vegetables, nuts) to improve overall sperm health.

- Hydration: Ensure adequate hydration, as dehydration can affect semen volume and quality.

- Exercise: Regular physical activity can improve hormonal balance and overall health, which may positively influence sperm production.

- Avoid Toxins: Limit exposure to environmental toxins, such as pesticides and heavy metals, and avoid smoking and excessive alcohol consumption.

2. Medical Evaluation:
- Infection Screening: Given the presence of WBCs, it may be beneficial to consult a urologist or a fertility specialist to rule out infections or inflammation in the reproductive tract. Tests may include semen culture or additional blood tests.

- Hormonal Assessment: Hormonal imbalances can also affect sperm production and quality. A healthcare provider may recommend testing testosterone and other hormone levels.

3. Follow-Up Semen Analysis: After implementing lifestyle changes and any medical treatments, a follow-up semen analysis may be warranted to assess improvements in liquefaction time and overall sperm parameters.

4. Consideration of Assisted Reproductive Techniques: If natural conception proves challenging, discussing options such as intrauterine insemination (IUI) or in vitro fertilization (IVF) with a fertility specialist may be appropriate.


Conclusion
In summary, while your sperm count and morphology are encouraging, the prolonged liquefaction time and motility issues warrant further investigation and potential lifestyle modifications. Addressing any underlying infections or inflammation is crucial for improving your fertility potential. Consulting with a healthcare provider specializing in male fertility can provide tailored advice and treatment options based on your specific situation.

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