Impact of Keflex on Pregnancy: Concerns About Bartholin Gland Cysts - Obstetrics and Gynecology

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Bartholin's cyst


Hello, I am currently preparing for pregnancy, but I experience swelling and pain in the Bartholin's glands after intercourse.
After my last sexual encounter, my doctor prescribed Keflex for me, and I have been taking it for a little over a week.
If I become pregnant, will it affect the fetus? Should I stop taking the medication? Thank you.

Li Li, 30~39 year old female. Ask Date: 2014/09/18

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, if you have been taking Keflex for over a week and are pregnant, it should not affect the fetus.
If the treatment is successful, you may consider stopping the medication.
Wishing you good health.

Reply Date: 2014/09/18

More Info


Keflex, known generically as cephalexin, is a type of antibiotic that belongs to the cephalosporin class. It is commonly prescribed to treat bacterial infections, including those affecting the urinary tract and skin. When it comes to pregnancy, the safety of medications is a primary concern for expectant mothers and healthcare providers alike.

According to the FDA pregnancy categories, Keflex is classified as a Category B drug. This means that animal reproduction studies have not demonstrated a risk to the fetus, and there are no adequate and well-controlled studies in pregnant women. Therefore, if you have been prescribed Keflex for a Bartholin gland cyst infection, it is generally considered safe to use during pregnancy. However, it is always essential to consult with your healthcare provider regarding any medications you are taking, especially if you suspect you might be pregnant.

In your case, if you have been taking Keflex for over a week and are concerned about the potential impact on a developing fetus, it is reassuring to know that there is no evidence suggesting that Keflex would harm the fetus. If you do become pregnant while taking this medication, it is advisable to discuss your situation with your healthcare provider. They can provide personalized guidance based on your health history and the specifics of your pregnancy.

Regarding the Bartholin gland cysts, these are fluid-filled sacs that can develop in the Bartholin glands, which are located on either side of the vaginal opening. While they can cause discomfort or pain, especially during sexual intercourse, they typically do not pose a risk to the fetus. However, if the cyst becomes infected, it may require treatment, such as antibiotics like Keflex, to prevent complications.

If you are experiencing persistent pain or swelling in the Bartholin glands, it is crucial to follow up with your healthcare provider. They may recommend further evaluation or treatment options, which could include drainage of the cyst if it is causing significant discomfort or recurrent infections.

In summary, taking Keflex during the early stages of pregnancy is generally considered safe, and it is unlikely to affect fetal development negatively. However, it is always best to have an open dialogue with your healthcare provider about any medications you are taking and any concerns you may have regarding your health and pregnancy. They can help you weigh the benefits and risks and make informed decisions about your treatment plan. If you are experiencing symptoms related to Bartholin gland cysts, continue to seek medical advice to ensure your comfort and health during this important time.

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