Life Expectancy in Advanced Prostate Cancer: Key Insights - Urology

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My father is currently in the fourth stage of prostate cancer and is under hormone therapy.
His diet consists of a large amount of fruits and vegetables, in addition to fish and meat.
Last week, his PSA level was 10.
Since his diagnosis about two months ago, he has not experienced any physical abnormalities; urination is smooth without frequency, and he has no pain.
The only issue is that he wakes up twice at night to use the bathroom.
Doctor, could you please provide an estimate of his life expectancy under these circumstances? Are there any relevant studies or data available both domestically and internationally that I can refer to? I often find myself unable to sleep due to worrying about this...
Thank you, doctor!

A Dong, 30~39 year old female. Ask Date: 2015/01/12

Dr. Liu Jiaju reply Urology


When a loved one is diagnosed with cancer, family members often worry about their potential life expectancy.
However, the length of life expectancy is influenced by many factors, including the stage of cancer, the individual's overall health, and their response to treatment.
It is advisable to have a detailed discussion with the treating physician to obtain a more accurate estimate.

Reply Date: 2015/01/12

More Info


Understanding life expectancy in advanced prostate cancer, particularly in stage IV, is a complex issue that depends on various factors. Your father's situation, where he is currently undergoing hormone therapy and has a PSA level of 10, indicates that he is being monitored and treated for his condition. While it is natural to be concerned about life expectancy, it is essential to understand that each patient's case is unique, and many variables can influence outcomes.

In general, the prognosis for stage IV prostate cancer can vary widely. Factors that can affect life expectancy include the patient's overall health, response to treatment, the presence of metastasis (spread of cancer to other parts of the body), and the specific characteristics of the cancer itself. Studies have shown that patients with advanced prostate cancer who respond well to hormone therapy can live for several years, while others may have a shorter life expectancy.

According to the American Cancer Society, the five-year relative survival rate for men diagnosed with stage IV prostate cancer is approximately 30%. However, this statistic is based on data from a broad population and does not account for individual circumstances. Some patients may live much longer than five years, especially if they respond well to treatment and maintain a good quality of life.

Your father's current health status, including the absence of significant symptoms such as pain or urinary issues, is a positive sign. The fact that he is eating a healthy diet rich in fruits and vegetables, along with fish, can also contribute to his overall well-being. Nutrition plays a crucial role in cancer care, and a balanced diet can help support the body's immune system and overall health.

Regarding the PSA level, a PSA of 10 indicates that there is still some level of prostate cancer activity, but it is essential to monitor how this number changes over time. PSA levels can fluctuate due to various factors, including treatment response and other non-cancerous conditions. Regular monitoring and follow-up with his healthcare provider will be crucial in assessing his condition.

As for studies and research, there are numerous clinical trials and studies that focus on advanced prostate cancer treatment and outcomes. These studies often provide insights into the effectiveness of various therapies, including hormone therapy, chemotherapy, and newer treatments like immunotherapy. Engaging with healthcare professionals who are knowledgeable about the latest research can provide valuable information tailored to your father's specific situation.

It is also important to address the emotional and psychological aspects of dealing with a cancer diagnosis. Anxiety and stress are common among patients and their families. Seeking support from mental health professionals, support groups, or counseling can be beneficial for both your father and your family as you navigate this challenging time.

In conclusion, while it is difficult to predict an exact life expectancy for your father, many factors will influence his prognosis. Regular follow-ups with his healthcare team, adherence to treatment, and maintaining a healthy lifestyle can all contribute to a better outcome. It is essential to have open discussions with his doctors to understand his specific situation better and to seek support for the emotional challenges that arise during this journey.

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