and Treating Winter-Triggered Cholinergic Urticaria - Dermatology

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How should it be treated?


Hello, doctor! I have been experiencing this symptom for several years, and it only occurs in winter.
After eating hot foods, such as noodle soup or hot soup, I feel a prickling itch on my back that lasts about 5 minutes before easing off.
There are no visible rashes, but I have a strong urge to take off my clothes because it feels more comfortable that way! I would like to know if this is what is referred to as cholinergic urticaria (heat allergy)? Recently, I noticed that if I exercise and sweat a little before meals or eat right after taking a shower, this symptom rarely appears.
I also have keratosis pilaris, and I would like to ask if this symptom worsens in winter, potentially leading to sweat gland blockage and resulting in heat allergy? I have consulted some fellow patients with heat allergy, and they mentioned that exercising and sweating can help alleviate this symptom.
Could you please provide me with answers and recommendations for dermatological medications?

A-Jia, 20~29 year old female. Ask Date: 2015/02/18

Dr. Wu Yuxin reply Dermatology


It is indeed likely cholinergic urticaria.
Dermatologists can help you with treatment, but whether aggressive treatment is necessary depends on the severity and frequency of the episodes, so it should be discussed during your appointment.
The primary treatment generally involves oral antihistamines.

Reply Date: 2015/02/18

More Info


Cholinergic urticaria (CU) is a type of hives that is triggered by an increase in body temperature, which can occur due to various factors such as exercise, hot showers, or consuming hot foods. Your symptoms, which include a prickling sensation on your back after eating hot foods, align with this condition. The fact that you experience these symptoms primarily in winter may be related to the contrast between the cold environment and the heat generated by the food, which can provoke an exaggerated response from your body.

In cholinergic urticaria, the body releases histamines in response to triggers, leading to itching, burning, or prickling sensations, often without visible hives. This can be particularly frustrating, as you noted that there are no visible rashes, yet the discomfort is significant enough to make you want to remove your clothing for relief. The duration of your symptoms, around five minutes, is typical for CU, as the body usually returns to its baseline state relatively quickly once the trigger is removed.

Your observation that exercising before meals or showering before eating reduces the frequency of these symptoms is interesting. Exercise can help improve circulation and may enhance the body's ability to regulate temperature, potentially reducing the likelihood of an exaggerated histamine response. Additionally, if you are sweating, it may help to alleviate the symptoms by providing a cooling effect on your skin.

Regarding your concern about keratosis pilaris (often referred to as "chicken skin"), it is a common skin condition that causes small, rough bumps, usually on the arms, thighs, and sometimes the back. While keratosis pilaris itself does not directly cause cholinergic urticaria, individuals with skin conditions may have more sensitive skin, which could potentially exacerbate the sensations associated with CU. However, there is no direct evidence to suggest that keratosis pilaris leads to cholinergic urticaria or that it causes sweat gland blockage.

For treatment, antihistamines are typically the first line of defense for cholinergic urticaria. Non-sedating antihistamines, such as cetirizine or loratadine, can be effective in managing symptoms. In some cases, your healthcare provider may recommend a higher dose or a combination of antihistamines to achieve better control of your symptoms. It's also important to avoid known triggers when possible, such as hot foods or environments that may cause your body temperature to rise rapidly.

If your symptoms persist or worsen, it may be beneficial to consult a dermatologist or an allergist for further evaluation. They can provide tailored advice and may suggest additional treatments, such as topical corticosteroids or other medications that can help manage your symptoms more effectively.

In summary, your symptoms are consistent with cholinergic urticaria, and while they can be uncomfortable, there are effective management strategies available. Maintaining a dialogue with your healthcare provider about your symptoms and treatment options is essential for finding the best approach for your situation.

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