How Long Can HPV Lesions Persist Without Treatment? - Urology

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If cauliflower lesions are left untreated, how long will they persist?


In August 2014, I was diagnosed with genital warts in the obstetrics and gynecology department.
At that time, I had been married for three years.
The gynecologist advised my husband to get tested as well, and he was also diagnosed with genital warts.
However, he told me that his infection was transmitted to him by a former girlfriend, and he claimed that the lesion (about the size of half a grain of rice) had been present for several years, indicating that he was not unfaithful to me after our marriage.
Is it possible for a lesion to exist for that long without disappearing or spreading? Thank you, doctor.

Huái yí bèi piàn de shǎ nǚ rén, 30~39 year old female. Ask Date: 2015/03/30

Dr. Li Xinyi reply Urology


Although the situation you described is less common, it is not impossible.
Each person's response to the virus can vary.
In medicine, you may not find the answers you are looking for.

Reply Date: 2015/03/30

More Info


HPV (Human Papillomavirus) is a common sexually transmitted infection that can lead to various health issues, including genital warts (commonly referred to as "cauliflower" or "condyloma acuminata") and, in some cases, cervical cancer. Understanding how long HPV lesions can persist without treatment is crucial for both patients and their partners.

Firstly, it is essential to recognize that HPV infections can behave quite differently from other viral infections. In many cases, the immune system can clear the virus naturally within two years. However, some individuals may experience persistent infections, which can lead to the development of lesions or warts. The persistence of these lesions can vary significantly among individuals due to factors such as immune response, the specific strain of HPV, and overall health.

In your case, your husband's lesion has reportedly been present for several years without treatment. This scenario is not uncommon. Some HPV strains can remain dormant in the body for extended periods, sometimes even years, before manifesting as visible lesions. The fact that your husband has had a lesion for several years suggests that he may have a persistent HPV infection. It's also possible that he was infected before your relationship, which aligns with his statement regarding his previous partner.

The persistence of HPV lesions without treatment can be attributed to several factors:
1. Immune Response: Some individuals have a robust immune response that can control the virus, preventing the development of new lesions. Others may have a weaker immune response, allowing the virus to persist and cause lesions.

2. Type of HPV: There are over 200 types of HPV, and some are more likely to cause persistent infections and lesions than others. High-risk types are often associated with cancer, while low-risk types are typically linked to warts.

3. Health and Lifestyle Factors: Factors such as stress, smoking, and overall health can impact the immune system's ability to fight off HPV. Individuals with compromised immune systems (due to conditions like HIV or medications that suppress immunity) are more likely to experience persistent infections.

4. Lesion Characteristics: The size and appearance of lesions can also vary. Some may remain small and stable for years, while others can grow or multiply.

Regarding your question about whether a lesion can exist for years without disappearing or spreading, the answer is yes. HPV lesions can remain stable for extended periods, and while they may not always lead to further complications, they can still be contagious. This means that even if the lesions do not change, the virus can still be transmitted to sexual partners.

In terms of treatment, it is important to consult with a healthcare provider for proper evaluation and management. Treatments for HPV lesions include topical medications, cryotherapy, laser therapy, and surgical removal. While these treatments can remove visible lesions, they do not eliminate the virus from the body. Therefore, even after treatment, there is a possibility of recurrence.

In conclusion, HPV lesions can persist for years without treatment, and the duration can vary based on individual immune responses and the specific HPV type. It is crucial to maintain open communication with partners about HPV status and to seek medical advice for appropriate management and treatment options. Regular check-ups and screenings are also essential for monitoring any changes and ensuring overall reproductive health.

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