Constipation and Urgency from Long-term Sedative Use - Gastroenterology and Hepatology

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Taking tranquilizers?


Hello Doctor: I am 48 years old and started taking anxiolytics eight years ago, which led to constipation, having a bowel movement about once a week.
I didn't pay much attention to it, but about five or six years ago, I began experiencing urgent bowel movements at times.
If I'm outside, it can be quite embarrassing, but fortunately, I'm usually close to home and can rush back to use the bathroom.
What is happening to me?

Mr. Zhang, 40~49 year old female. Ask Date: 2015/04/15

Dr. Chen Qifeng reply Gastroenterology and Hepatology


Hello: The use of anxiolytics often leads to decreased gastrointestinal motility in most patients, resulting in constipation.
For these situations, it is recommended to increase the intake of fruits, vegetables, and fluids.
If improvement is not achieved, a consultation with a gastroenterologist may be necessary for medication.
Wishing you peace and health.
Dr.
Chen Chih-Feng, Gastroenterology Department, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2015/04/15

More Info


Constipation and urgency can be challenging symptoms, especially when they arise from long-term use of sedative medications, such as benzodiazepines or other anxiolytics. Your experience of having constipation for several years, followed by episodes of urgency, suggests a complex interplay between your medication, gastrointestinal (GI) function, and possibly other underlying factors.


Understanding the Symptoms
1. Constipation: Sedative medications can slow down the gastrointestinal motility, leading to constipation. This is because these drugs often have anticholinergic effects, which can inhibit the normal contractions of the intestines. When bowel movements become infrequent (like once a week), it can lead to harder stools, discomfort, and a feeling of incomplete evacuation.

2. Urgency: The sudden need to have a bowel movement can be distressing, especially if it occurs when you are away from home. This urgency may be related to several factors:
- Irritable Bowel Syndrome (IBS): Some individuals develop IBS, which can manifest as alternating constipation and diarrhea, along with urgency.

- Medication Effects: Some sedatives can also affect the gut-brain axis, potentially leading to changes in bowel habits.

- Psychological Factors: Anxiety or stress can exacerbate GI symptoms, leading to urgency.


Recommendations
1. Consult a Healthcare Provider: It's crucial to discuss your symptoms with a healthcare professional, preferably a gastroenterologist. They can evaluate your symptoms in detail, possibly perform diagnostic tests (like a colonoscopy or imaging studies), and rule out other conditions such as inflammatory bowel disease or colorectal issues.

2. Medication Review: A thorough review of your current medications is essential. Your doctor may consider adjusting your sedative dosage or switching to a different class of medication that has fewer gastrointestinal side effects.
3. Dietary Changes: Increasing fiber intake through fruits, vegetables, and whole grains can help alleviate constipation. Additionally, staying well-hydrated is crucial. If you are not already doing so, consider incorporating more fluids into your daily routine.

4. Physical Activity: Regular exercise can stimulate bowel function and help alleviate constipation. Even moderate activities like walking can be beneficial.

5. Over-the-Counter Solutions: If dietary changes are insufficient, your doctor may recommend over-the-counter laxatives or stool softeners. However, these should be used cautiously and under medical supervision, especially if you have been experiencing chronic constipation.

6. Behavioral Techniques: If urgency is a significant concern, behavioral techniques such as scheduled bathroom visits or pelvic floor exercises may help manage symptoms.


Conclusion
Your symptoms of constipation and urgency are likely interconnected and may be exacerbated by the long-term use of sedative medications. It is essential to address these issues with a healthcare provider who can help tailor a management plan that considers your overall health, medication regimen, and lifestyle. Remember, you are not alone in this, and there are effective strategies to improve your bowel health and quality of life.

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